Potentiometric Titration Technique - A Pressing Priority for High-Quality Output

Potentiometric Titration Technique - A Pressing Priority for High-Quality Output

By Knowledge Sourcing Intelligence Blog

The global potentiometric titration market is projected to grow at a CAGR of 6.21% during the forecast period. Potentiometric titration is a method that is used to determine the concentration of a given chemical. The potentiometric titration technique is widely used in the pharmaceutical industry to analyze the final concentration of the medicines or characterizing acids. This technique uses an indicator electrode that can record the change of the potential of the added titrant of exactly known concentration. The potentiometric titration technique is considered one of the most consistent and robust techniques among the non-NMR methods. Additionally, this method was among the first methods used to investigate the speciation of heteropoly acids, which involves measuring the concentration of hydrogen ions in polyanion solutions as a function of the added acid or base. Furthermore, this process is used by the research and development labs in pharmaceuticals, petrochemicals, personal care, chemical, and food and beverage industries. Such extensive use of the Potentiometric titration techniques is likely to drive profits for the market players.

Analysts anticipate that the global potentiometric titration market will rise due to its widespread importance across different industry vertices.

The potentiometric titration method is the most common laboratory method which is widely used in the pharmaceutical industry. The method is commonly used as the weight percent assay for small-molecule active pharmaceutical ingredients (APIs), raw materials, and intermediates. Furthermore, this method is also applicable to determine the salt ratio and ionization state of a drug compound in the pharmaceutical industry. For example, this method can be used to determine the amount of sugar or sole in a particular product or drug. The titration technique used chemical analysis to determine the complete concentration in the final solution. On a wider basis, this is also a quality control process that is used in research and development labs, and for finished products in pharmaceuticals, petrochemicals, chemicals, etc.

Additionally, the potentiometric titration test results are vital to control variation and reduce the risk during the drug manufacturing process. Metrohm, one of the world’s most trusted high-precision instrument manufacturers addresses the importance of the potentiometric titration technique in the pharmaceutical sector. It mentions that among many other tests which are used to characterize a formulation, potentiometric titration is one of the most reliable, fastest, and most economical techniques.  These significant benefits of using potentiometric titration techniques are expected to drive the market growth

Furthermore, cationic surfactants are used as disinfectants, bactericides, and also in the personal care industry. The rising demand for disinfectants in personal care and hygiene products has led to the misuse or overuse of these products. Consequently, this created a need to track down the use of cationic surfactants in these personal care products. The titration technique can determine the cationic surfactants’ contents. And thus, the potentiometric titration technique, which is new, fast, sensitive yet affordable has witnessed an increase in demand.

The varied opportunities for automation at every step of potentiometric titration have allowed the market to grow exponentially.

The rising research and development projects along with automation are aiding the growth of the global potentiometric titration market. The automation of the titration process allows it to opt for the different forms of dosage, analytes, and goals needed to ensure tight control of the raw materials used along with the quality of the finished pharmaceutical products with less human intervention. The reduced human intervention also improves accuracy and reduces the waste of time and materials that otherwise would have occurred due to human errors. It also allows increased throughput of the analytical lab. For instance, in 2019 Metrohm launched OMNIS titration which allows the users to consolidate all the titration applications on a single platform. The OMNIS titration enables the user to customize and automate its operations to ensure efficiency and safety. The modular design of this potentiometric titration device also allows the user to scale up the titration system to perform up to five parallel titrations. The company claims that this new OMNIs titration can save up to 60% of the time. Such technological advances and automation in the global potentiometric titration market are further escalating market growth.

Additionally, the researchers are focusing their efforts to develop a potentiometric titration device with sophisticated features like an easy-to-use interface, and diagnostic equipment that will allow going beyond the limits of currently available functions such as autonomous calculations, end-point detection, titrant dispensing, etc. thus, the increasing use of automation in potentiometric titration market in all given industries are supporting the growth of this market.

According to regional analysis, the potentiometric titration market in the Asia Pacific is expected to hold a significant share during the projected period.

The global probiotics market is segmented into five regions based on geography: North America, South America, Europe, the Middle East, Africa, and the Asia Pacific. Due to the rising pharmaceutical industries in developing nations such as India and China, the Asia Pacific region is expected to increase significantly during the forecast period. The rapidly growing population, rising disposable income, and increased awareness of health care along with personal are the key drivers of demand in this region. In addition, the higher production of titration equipment in countries like Japan is aiding the potentiometric titration market growth in the Asia Pacific. For example, Japanese companies like Kyoto Electronics Manufacturing (KEM) Co. Ltd., Japan Aqua Co. Ltd., and many more currently offer automatic potentiometric titrators in their product portfolio. Additionally, Europe and American subcontinents are also leading the race with high manufacturing units in these regions.

COVID-19 Insights

The pandemic had a significant impact on the global potentiometric titration market owing to the adverse impact of the restrictions. The predominant effect of pandemic-related import export disruptions in major end-user industries of potentiometric titration techniques such as personal care, chemical, packaging, etc. As a result of changing consumer preferences towards essential goods and services during the pandemic, the demand for personal care, chemical, and packing industries declined. Therefore, it significantly affected the use of the potentiometric titration technique in the mentioned industries. On the other hand, the increased operating powers of the healthcare, chemical, and medicine industries aided the growth of pharmaceutical industries post-pandemic, which is aiding the growth of the global potentiometric titration market.