Global Clinical Trial Management System (CTMS) Market Size, Share, Opportunities, COVID-19 Impact, And Trends By Type (Enterprise CTMS, Site CTMS), By Delivery Mode (On-Premise, Cloud-Based), By Component (Software, Services), By End-User (Pharmaceutical And Biotechnology Companies, Contract Research Organizations, Medical Device Manufacturers, Others), And By Geography - Forecasts From 2022 To 2027

  • Published : Mar 2022
  • Report Code : KSI061612086
  • Pages : 100

The global clinical trial management system (CTMS) market was valued at US$1,208.391 million in 2020 and is expected to grow at a CAGR of 12.51% over the forecast period to reach a total market size of US$2,757.691 million by 2027.

The Clinical Trial Management System (CTMS) is a software system used by the biotechnology and pharmaceutical industries to handle clinical trials in clinical research. The system keeps track of and handles planning, performance, and reporting tasks, as well as participant contact information and deadlines and milestones. ClinicalTrials currently lists 391,704 studies with sites in all 50 states and 219 countries.

The increased prevalence of chronic and lifestyle-related disorders, as well as a surge in clinical trial outsourcing and implementation by contract research companies, are driving market expansion. According to the Food and Agriculture Organization (FAO), chronic diseases will account for nearly three-quarters of all deaths worldwide by 2020, with developing countries accounting for 71% of deaths due to ischaemic heart disease (IHD), 75% of deaths due to stroke, and 70% of deaths due to diabetes. Diabetics will increase more than 2.5 times in the developing world, from 84 million in 1995 to 228 million in 2025. Globally, developing nations will bear 60% of the burden of chronic disorders. Furthermore, according to the World Health Organization 2020, major chronic illnesses such as heart disease, stroke, cancer, diabetes, and chronic lung disease account for about 70% of all fatalities globally. Almost three-quarters of all non-communicable disease (NCD) deaths occur in low- and middle-income countries, as do 82% of the 16 million individuals who died prematurely, or before reaching the age of 70.

Furthermore, increasing innovative technology developments to reduce the rising cost of clinical trials have resulted in the development of the clinical trial management system. Although these systems have not been fully adopted owing to a variety of reasons, increasing awareness and the desire to reduce additional expenses associated with clinical trials are likely to boost the market in the future. However, data security concerns and the high cost of clinical trial administration systems are expected to limit market development.

The overall clinical trial management systems market is projected to be dominated by North America. Factors such as increased R&D spending and an increase in demand for medication development are assisting in the expansion of the country's industry under study. According to WHO, 147,213 trials took place in the United States in 2020, which was the highest for any country, followed by 23,051 trials in China and 13,481 in Japan. The growing number of studies and clinical trials, along with increased financing for clinical research, is expected to fuel market growth.

Growth Factors

  • A Growing Number of Clinical Trials:

The increasing number of clinical trials, combined with the availability of sophisticated CTMS systems, is expected to drive market growth. According to WHO, there have been 61,311 trials worldwide in 2020, with a cumulative total of 600,173 trials since 1999. Thus, the increasing number of clinical research studies will boost the use of clinical trial management system solutions, therefore increasing market value. Furthermore, the demand for effective data management and clinical trial result analysis are a few other aspects that are expected to add to market revenue. The deployment and expense of a clinical trial management system, on the other hand, may hinder the market’s development.


Budget constraints and high cost Due to limited private financing, stringent regulations, and a bleak financial future, small and mid-sized client facilities frequently encounter budgetary restrictions for clinical trials. Ineffective site selection, poor research design and trial execution, safety concerns, and dropouts due to practical or budgetary constraints are additional instances. Furthermore, the amount of time and money necessary to finish a study grows with each phase. The overall cost of a Phase III failure includes the costs of all previous stages as well as the time that might have been spent testing an alternative medication. According to WHO, as of 2020, 62,603 trials are in Phase III development. Small pharma companies (those with less than $500 million in annual revenue) now account for more than 70% of the roughly 3,000 medicines in phase III clinical trials. Only approximately 20% of medicines now in phase III clinical trials have been launched by large pharma companies (those with annual revenues of $1 billion or more). Each failed study adds to the ever-increasing costs of biopharma R&D.  The Congressional Budget Office estimates that in 2019, the pharmaceutical sector spent $83 billion on research and development. The projected cost of developing new medication, including capital expenses and spending on drugs that do not reach the market, ranges from less than $1 billion to more than $2 billion.

COVID-19's Impact on the Clinical Trial Management System (CTMS) Market:

In the midst of the COVID-19 pandemic, the healthcare systems of countries are quickly investing in research and development to battle the virus. Potential chemicals were selected from the CHEMBL and ZINC databases, as well as FDA-approved medicines and molecules in clinical studies. As a result, COVID-19 is projected to have a favorable influence on market growth throughout the forecast period. Cytel Inc. deployed an open-access global COVID-19 Clinical Trial Tracker in April 2020, facilitating massive cooperation among academics, policymakers, doctors, journalists, philanthropists, and other important stakeholders. Similarly, asthe battle to discover an easy-to-administer therapy for the potentially deadly infection heats up, Pfizer Inc and Merck & Co Inc launched additional studies of their investigational oral antiviral medicines for COVID-19 in September 2021.

Key Developments

  • September 2021:  PHARMASEAL International Ltd. and Medrio, Inc. collaborated to integrate Medrio's eClinical data collection suite with PHARMASEAL's trial management platform, Englity®.
  • August 2021:  Verily, an Alphabet subsidiary, has agreed to acquire SignalPath, a clinical trial management system (CTMS) based in Raleigh, North Carolina, that improves the accessibility, quality, and efficiency of clinical research at study sites.

Global Clinical Trial Management System (CTMS) Market Scope:

Report Metric Details
 Market size value in 2020  US$1,208.391 million
 Market size value in 2027  US$2,757.691 million
 Growth Rate  CAGR of 12.51% from 2020 to 2027
 Base year  2020
 Forecast period  2022–2027
 Forecast Unit (Value)  USD Million
 Segments covered  Type, Delivery Mode, Component, End-User, And Geography
 Regions covered  North America, South America, Europe, Middle East and Africa, Asia Pacific
 Companies covered ArisGlobal LLC, RealTime Software Solutions LLC, Breeze CTMS, Veeva Systems, Oracle Corporation, Business Systems Integration AG, Ennov, Bioclinica, IBM Corporation, Bio-Optronics Inc.
 Customization scope  Free report customization with purchase


Market Segmentation

  • By Type
    • Enterprise CTMS
    • Site CTMS
  • By Delivery Mode
    • On-premise
    • Cloud-based
  • By Component
    • Software
    • Services
  • By End-User
    • Pharmaceutical and Biotechnology Companies
    • Contract Research Organizations
    • Medical Device Manufacturers
    • Others
  • By Geography
    • North America
      • USA
      • Canada
      • Mexico
    • South America
      • Brazil
      • Argentina
      • Others
    • Europe
      • Germany
      • France
      • UK
      • Italy
      • Spain
      • Others
    • Middle East and Africa
      • Saudi Arabia
      • UAE
      • South Africa
      • Others
    • Asia Pacific
      • China
      • India
      • Japan
      • South Korea
      • Taiwan
      • Thailand
      • Indonesia
      • Others

Frequently Asked Questions (FAQs)

Q1. What are the growth prospects for the clinical trial management system market?
A1. The global clinical trial management system (CTMS) market is expected to grow at a CAGR of 12.51% during the forecast period.

Q2. What will be the clinical trial management system (CTMS) market size by 2027?
A2. The clinical trial management system market is expected to reach a market size of US$2,757.691 million by 2027.

Q3. What is the size of the global clinical trial management system (CTMS) market?
A3. Clinical Trial Management System (CTMS) Market was valued at US$1,208.391 million in 2020. 

Q4. Which region holds the maximum market share in the clinical trial management system market?
A4. The North American region is projected to dominate the clinical trial management system market due to the factors such as increased R&D spending and an increase in demand for medication development.

Q5. What factors are anticipated to drive the clinical trial management system (CTMS) market growth?
A5. The increasing number of clinical trials, combined with the availability of sophisticated CTMS systems, is expected to drive clinical trial management system market growth.

1. Introduction
1.1. Market Definition
1.2. Market Segmentation

2. Research Methodology
2.1. Research Data
2.2. Assumptions

3. Executive Summary
3.1. Research Highlights

4. Market Dynamics
4.1. Market Drivers
4.2. Market Restraints
4.3. Porters Five Forces Analysis
4.3.1. Bargaining Power of End-Users
4.3.2. Bargaining Power of Buyers
4.3.3. Threat of New Entrants
4.3.4. Threat of Substitutes
4.3.5. Competitive Rivalry in the Industry
4.4. Industry Value Chain Analysis

5. Global Clinical Trial Management System (CTMS) Market Analysis, by Type
5.1. Introduction
5.2. Enterprise CTMS
5.3. Site CTMS

6. Global Clinical Trial Management System (CTMS) Market Analysis, by Delivery Mode
6.1. Introduction
6.2. On-premise
6.3. Cloud-based

7. Global Clinical Trial Management System (CTMS) Market Analysis, by Component
7.1. Introduction
7.2. Software
7.3. Services

8. Global Clinical Trial Management System (CTMS) Market Analysis, by End-User
8.1. Introduction
8.2. Pharmaceutical and Biotechnology Companies
8.3. Contract Research Organizations
8.4. Medical Device Manufacturers
8.5. Others

9. Global Clinical Trial Management System (CTMS) Market Analysis, by Geography
9.1. Introduction
9.2. North America
9.2.1. USA
9.2.2. Canada
9.2.3. Mexico
9.3. South America
9.3.1. Brazil
9.3.2. Argentina
9.3.3. Others
9.4. Europe
9.4.1. Germany
9.4.2. France
9.4.3. UK
9.4.4. Italy
9.4.5. Spain
9.4.6. Others
9.5. Middle East and Africa
9.5.1. Saudi Arabia
9.5.2. UAE
9.5.3. South Africa
9.5.4. Others
9.6. Asia Pacific
9.6.1. China
9.6.2. India
9.6.3. Japan
9.6.4. South Korea
9.6.5. Taiwan
9.6.6. Thailand
9.6.7. Indonesia
9.6.8. Others

10. Competitive Environment and Analysis
10.1. Major Players and Strategy Analysis
10.2. Emerging Players and Market Lucrativeness
10.3. Mergers, Acquisitions, Agreements, and Collaborations
10.4. Vendor Competitiveness Matrix

11. Company Profiles 
11.1. ArisGlobal LLC
11.2. RealTime Software Solutions LLC
11.3. Breeze CTMS
11.4. Veeva Systems
11.5. Oracle Corporation
11.6. Business Systems Integration AG
11.7. Ennov
11.8. Bioclinica
11.9. IBM Corporation
11.10. Bio-Optronics Inc.

ArisGlobal LLC

RealTime Software Solutions LLC

Breeze CTMS

Veeva Systems

Oracle Corporation

Business Systems Integration AG



IBM Corporation

Bio-Optronics Inc.