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Organ-on-a-Chip Technologies Market - Forecasts From 2023 To 2028

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Report Overview

The organ-on-a-chip technologies market is a game-changing invention in biomedical research and medicine development. This innovative technique entails the development of microfluidic devices that mirror the shape and function of human organs, providing a highly realistic and dynamic platform for investigating biological processes. These "organs-on-a-chip" allow researchers to examine cellular reactions and interactions in a controlled setting, more faithfully reproducing the intricacies of human physiology than standard cell culture or animal models. Organ-on-a-Chip technologies have the potential to revolutionise drug testing, personalised therapy, and the knowledge of human illnesses by offering insights into medication effectiveness, toxicity, and disease causes. The organ-on-a-chip technologies market is positioned for enormous growth and effect on the future of healthcare due to its capacity to speed medication development and lessen reliance on animal testing.

Organ-on-a-Chip Technologies Market - Highlights
In September 2022,
Emulate, Inc., a leading provider of next-generation in vitro models, today announced the release of its new adeno-associated virus (AAV) transduction application for the Liver-Chip, which allows gene therapy researchers to test the delivery efficiency and safety of AAV vectors in a validated, human-relevant model of the liver in weeks, rather than months, as with animal models. This method enables them to rapidly iterate on AAV design in order to optimise gene therapy delivery and speed development.
In June 2021,
PMI and TissUse have struck a collaboration to use PMI's InHALES technology in conjunction with TissUse's patented Multi-Organ-Chip (MOC) platform to enable in vitro inhalation exposure of functioning human tissues in homeostasis. The two companies will collaborate to create a highly creative integrated human aerosol test platform that, in terms of dimension and design, mimics the whole human respiratory system. PMI has developed a platform that closely resembles the design and properties of the human respiratory system (InHALES).
In March 2023,
VUB and InSphero AG, a leading producer of 3D in vitro liver disease models, have announced a licencing agreement for the development and marketing of a non-alcoholic steatohepatitis (NASH) in vitro model. VUB's renowned experience in liver biology and NASH research is combined with InSphero's market-leading, scalable 3D cell culture technology for drug development. The end product is a cutting-edge in vitro model that will speed up treatment development for NASH, a fast-rising worldwide health concern. The model is the market's only scalable, automation-compatible system that spans the whole development process, from screening for novel compounds against NASH through mechanistic analysis of screening findings.

Advancements in Microfluidics and Tissue Engineering Enhances the Organ-on-a-Chip Technologies Market Growth.

Microfluidics and tissue engineering advancements have transformed the organ-on-a-chip technologies market. These technologies have aided in the creation of small devices that more closely imitate the physiological conditions of human organs than standard cell cultures or animal models. Microfluidics allows researchers to develop dynamic and realistic in vitro models of human organs by providing precise control over fluid flow and cell interactions. Integration with tissue engineering techniques enables the formation of functioning three-dimensional tissue structures, improving the mimicry of human physiology even further. These innovations have sped up drug development, personalised medicine, and disease modelling, fuelling the market's growth and the potential to change how pharmaceuticals are produced and tested in the future.

Potential to Reduce Animal Testing in Drug Development in Organ-on-a-Chip Technologies Market.

The organ-on-a-chip technologies market has the potential to significantly minimise animal testing in medication development. Organ-on-a-chip technologies provide an ethical and more accurate alternative to traditional animal research by creating extremely realistic and physiologically appropriate in vitro models of human organs. Researchers may undertake pharmacological effectiveness and safety investigations on human cells, more accurately recreating organ interactions and reactions. This lowers reliance on animal models and aligns drug testing with human biology, resulting in greater drug outcome prediction. As the quest for more ethical and efficient drug discovery continues, the market for organ-on-a-chip technology is projected to rise, benefiting both patients and researchers.

Enhanced In Vitro Modelling of Human Physiology Boosts the  Organ-on-a-Chip Technologies Market Size.

The improved in vitro modelling of human physiology enabled by organ-on-a-chip technologies is a game changer in biomedical research. These technologies enable the development of microscale devices that closely resemble the structure and functions of human organs. Researchers may examine dynamic cellular interactions, tissue responses, and disease causes in a controlled setting by culturing human cells within these chips. This enhanced modelling delivers unparalleled insights into human physiology, medication reactions, and disease development, making drug testing and personalised therapy more reliable and predictive. Organ-on-a-chip technologies have enormous promise to speed medical discoveries and revolutionise drug development procedures as they perfect in vitro human modelling.

North America is the Market Leader in the Organ-on-a-Chip Technologies Market.

North America was regarded as the market leader in organ-on-a-chip technologies market. The popularity of this region may be due to its strong emphasis on R&D, well-established biotechnology and pharmaceutical sectors, and large expenditures in cutting-edge technologies. Several significant firms, academic institutions, and research centres in North America are actively involved in the development and commercialization of Organ-on-a-Chip technology. Furthermore, the region's favourable regulatory framework and cooperation between academics and business have aided in the advancement and quick acceptance of this novel technology. However, market dynamics may have altered the organ-on-a-chip technologies market's leading region.

Increasing Focus on Disease Modelling and Drug Safety Assessment in Organ-on-a-Chip Technologies Market.

Disease modelling and medication safety evaluation are becoming increasingly important in the organ-on-a-chip technologies market. Researchers may reproduce illness circumstances by constructing microscale organ replicas with human cells, allowing them to examine disease processes and treatment responses in vitro. This technique provides a more precise and dependable platform for assessing medication safety, allowing researchers to discover possible toxicities and side effects early in the drug development process. The capacity to model illness progression and medication interactions in a controlled setting improves predictive skills, resulting in more efficient and informed drug development decision-making. The use of organ-on-a-chip technologies for disease modelling and medication safety evaluation is becoming increasingly important as the emphasis on precision medicine and personalised therapeutics rises.

Key Developments:

Company Products:

  • Nortis Microfluidic Chips: Nortis created microfluidic chips that allowed human cells to be cultured in three dimensions to replicate the shape and function of numerous organs. These chips provided a highly regulated and realistic environment for researchers to examine human physiology, disease processes, and medication reactions.
  • OrganoPlate®: MIMETAS created the OrganoPlate®, a one-of-a-kind microfluidic technology that enabled the cultivation of several organ models on a single chip. Researchers were able to explore organ interactions and systemic reactions using this technology in a high-throughput and cost-effective manner.
  • Multi-Organ-Chips: TissUse created Multi-Organ-Chips, which are advanced microfluidic devices that can hold many linked organ modules, allowing researchers to examine organ interconnections and systemic reactions. These chips enable researchers to recreate more complicated physiological circumstances and disease models, improving medication testing and toxicity evaluations.
  • Organ-Chips: Organ-Chips are microfluidic devices containing living human cells organised to replicate the form and function of certain organs such as the lung, liver, kidney, and intestine. Researchers may investigate human physiology and illness using these chips in a more physiologically appropriate and dynamic setting than standard cell cultures or animal models.

Segmentation:

  • By Organ Type
    • Liver-On-A-Chip
    • Heart-On-A-Chip
    • Lung-On-A-Chip
    • Kidney-On-A-Chip
    • Intestine-On-A-Chip
    • Brain-On-A-Chip
    • Skin-On-A-Chip
    • Others   
  • By Application
    • Drug Discovery And Development
    • Toxicity Testing
    • Disease Modeling
    • Organ Regeneration
    • Personalized Medicine
    • Others 
  • By End-User
    • Pharmaceutical And Biotechnology Companies
    • Academic And Research Institutes
    • Contract Research Organizations (Cros)
    • Others               
  •  By Geography
    • North America
      • United States
      • Canada
      • Mexico
    • South America
      • Brazil
      • Argentina
      • Others
    • Europe
      • United Kingdom
      • Germany
      • France
      • Italy
      • Spain    
      • Others
    • Middle East and Africa
      • Saudi Arabia
      • UAE
      • Others
    • Asia Pacific
      • Japan
      • China
      • India
      • South Korea
      • Indonesia
      • Taiwan
      • Others

Table of Contents

1. INTRODUCTION

1.1. Market Overview

1.2. Market Definition

1.3. Scope of the Study

1.4. Market Segmentation

1.5. Currency

1.6. Assumptions

1.7. Base, and Forecast Years Timeline

2. RESEARCH METHODOLOGY  

2.1. Research Data

2.2. Sources

2.3. Research Design

3. EXECUTIVE SUMMARY

3.1. Research Highlights

4. MARKET DYNAMICS

4.1. Market Drivers

4.2. Market Restraints

4.3. Porters Five Forces Analysis

4.3.1. Bargaining Power of Suppliers

4.3.2. Bargaining Power of Buyers

4.3.3. Threat of New Entrants

4.3.4. Threat of Substitutes

4.3.5. Competitive Rivalry in the Industry

4.4. Industry Value Chain Analysis

5.  ORGAN-ON-A-CHIP TECHNOLOGIES MARKET, BY ORGAN TYPE

5.1. Introduction

5.2. LIVER-ON-A-CHIP

5.3. HEART-ON-A-CHIP

5.4. LUNG-ON-A-CHIP

5.5. KIDNEY-ON-A-CHIP

5.6. INTESTINE-ON-A-CHIP

5.7. BRAIN-ON-A-CHIP

5.8. SKIN-ON-A-CHIP

5.9. OTHERS    

6. ORGAN-ON-A-CHIP TECHNOLOGIES MARKET, BY APPLICATION

6.1. Introduction

6.2. DRUG DISCOVERY AND DEVELOPMENT

6.3. TOXICITY TESTING

6.4. DISEASE MODELING

6.5. ORGAN REGENERATION

6.6. PERSONALIZED MEDICINE

6.7. OTHERS  

7. ORGAN-ON-A-CHIP TECHNOLOGIES MARKET, BY END-USER

7.1. Introduction

7.2. PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES

7.3. ACADEMIC AND RESEARCH INSTITUTES

7.4. CONTRACT RESEARCH ORGANIZATIONS (CROS)

7.5. OTHERS               

7.6.  ORGAN-ON-A-CHIP TECHNOLOGIES MARKET, BY GEOGRAPHY

7.7. Introduction

7.8. North America

7.8.1. United States

7.8.2. Canada

7.8.3. Mexico

7.9. South America

7.9.1. Brazil

7.9.2. Argentina

7.9.3. Others

7.10. Europe

7.10.1. United Kingdom

7.10.2. Germany

7.10.3. France

7.10.4. Italy

7.10.5. Spain

7.10.6. Others

7.11. Middle East and Africa

7.11.1. Saudi Arabia

7.11.2. UAE

7.11.3. Others

7.12. Asia Pacific

7.12.1. Japan

7.12.2. China

7.12.3. India

7.12.4. South Korea

7.12.5. Indonesia 

7.12.6. Taiwan

7.12.7. Others

8. COMPETITIVE ENVIRONMENT AND ANALYSIS

8.1. Major Players and Strategy Analysis

8.2. Emerging Players and Market Lucrativeness

8.3. Mergers, Acquisitions, Agreements, and Collaborations

8.4. Vendor Competitiveness Matrix

9. COMPANY PROFILES

9.1. EMULATE, INC.

9.2. TISSUSE GMBH

9.3. HESPEROS, INC.

9.4. CN BIO INNOVATIONS LTD.

9.5. AXOSIM, INC.

9.6. NORTIS, INC.

9.7. INSPHERO AG

9.8. MIMETAS B.V.

9.9. CHERRY BIOTECH

9.10. MICRONIT MICROFLUIDICS B.V.        

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Organ-on-a-Chip Technologies Market Report

Report IDKSI061615810
PublishedJul 2023
Pages144
FormatPDF, Excel, PPT, Dashboard

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