Life Threatening Cancer and It’s Biomarker

Life Threatening Cancer and It’s Biomarker

By Knowledge Sourcing Intelligence Thought Articles

Over the projected timeframe, the global cancer profiling market is anticipated to grow at a compound annual growth rate of 15.67 percent, reaching a market size of US$49.176 billion in 2027, up from US$17.750 billion in 2020. Cancer is a disease in which certain cells grow maniacally and spread to the rest of the body. Cancer is a disease that can occur almost anywhere in the human body, containing trillions of cells. Human cells normally multiply rapidly to produce new cells as the body requires them. Cells die when old or damaged, and new cells replace them. Once this orderly process fails, damaged or abnormal cells grow and multiply, which should not happen. Tumors, which are tissue lumps, can form when these cells combine. Tumors can be cancerous or not (benign). Cancerous tumors intrude on nearby tissues and can commute to distant locations in the body to establish new tumors; the process is called metastasis. Cancerous tumors can be renowned as malignant tumors. Many cancers are sarcomas, but blood cancers, such as leukemias, are not sarcomas. Benign tumors do not infest or propagate into nearby tissues. They usually do not recur when benign tumors are eliminated; they usually do not recur, whereas cancerous tumors occasionally do. However, benign tumors can grow to be quite massive at times. Such benign brain tumors can cause serious ailments or be fatal.

The Targeted Therapies Are Driving the Market Growth for Cancer Profiling Globally

The growing demand for targeted therapy and point-of-care diagnostic testing is projected to augment the growth potential for market participants during the projected timeline. 

One of the biggest contributors to market growth in the overall cancer profiling market is the emergence of new cancer cases. The rising cancer burden can be determined by a variety of factors, such as population increase and aging and changes in the pervasiveness of specific cancer causes linked to economic and social development. According to World Health Organisation, Deaths cause by Cancer account for 10 million, which is approximately 1 in 6 deaths due to cancer globally. Cancer-causing viruses, such as hepatitis and human papillomavirus (HPV) account for roughly 30% of cancer cases in low- and lower-middle-income countries. The cancer death cases common in 2020 are Lung-1.80 million deaths, Colon and Rectum-916000 deaths, Liver -830000 deaths, Stomach-769000 deaths, and Breast- 685 000 deaths, respectively. Cancer varies from country to country; the most common cancer in 23 countries is Cervical Cancer. Every year 400, 000 children approximately develop cancer. Breast cancer is the commonest cancer in women and the most widespread cancer globally; in 2020, there were2.26 million new breast cancer cases in women. 

Cause Of Cancer

Cancer develops from converting normal cells into cancerous cells in a multi-stage system that advances from a pre-cancerous lesion to a Cancerous Growth. Cancer-causing gene mutations primarily affect three types of genes: proto-oncogenes, DNA repair genes, and tumor suppressor genes. These changes are often referred to as cancer "drivers."

Proto-oncogenes play an important role in normal cell proliferation and differentiation. When these genes are modified or become more active than usual, they could become oncogenes, allowing cells to grow and thrive when they should not. Tumor suppressor genes are also associated with cell growth and division control. Cells with certain mutations in tumor suppressor genes may divide erratically. DNA repair genes are associated with the repair of damaged DNA. Cells with mutants in these genes are more likely to develop increased mutations in other genes and chromosomal changes, such as chromosome deletions and duplications. These genetic changes, when combined, may end up causing the cells to become cancerous. In 2020, the global cancer burden was 19.3 million new cases and 10.0 million deaths. The total number of people surviving within five years of a previous cancer diagnosis is 50.6 million worldwide.

Types Of  Cancer

There are over 100 different types of cancer. Cancer types are commonly named after the tissue or organs where they form. Lung cancer, for instance, begins in the lung, whereas brain cancer begins in the brain. Cancers can also be classified based on the type of cell that gave rise to them, as in a squamous cell or an epithelial cell.

Types Of  Cancer

Carcinoma:-The most prevalent type of cancer is carcinoma. They are caused by epithelial cells covering the inside and outside body surfaces.  

Sarcomas:-Sarcomas are cancers that develop in the soft tissues and bones, such as muscle, lymph vessels, fat, blood vessels, and fibrous tissue.

Leukemia:-Leukemias are cancers that begin in the bone marrow's blood-forming tissue. These cancers do not develop into solid tumors. Instead, abnormal white blood cells crowd out normal blood cells in the blood and bone marrow.

Lymphoma:- This cancer starts in lymphocytes. These white blood cells fight infections as part of the immune system. The abnormal lymphocytes starts accumulating in lymph vessels, lymph nodes and other organs respectively.

Brain Tumors:-These tumors are named after the type of cell that formed them and the tumor's location in the central nervous system.         

The Asia Pacific Region Is Expected to See a Boost in the Cancer Profiling Market Owing to the Rise in the Cancer Incidence in the Region

North America is expected to dominate the global Cancer Profiling market. The rising incidence of cancer and the region's high growing adoption are the primary reasons for North America's preeminence. In terms of market share, Asia-Pacific is anticipated to witness the fastest growth. Asia-Pacific is expanding due to increased contract research organizations (CROs), a push for better medical services, and soaring cancer incidences.

Source: World Health Organization

COVID -19 Insight

The COVID-19 disease outbreak is not known to impact the cancer profiling market during the forecasted period. Because of the COVID-19 spread, there has been a dramatic decrease in cancer testing and diagnosis due to coronavirus-related initiatives and resources. Regrettably, several patients with COVID-19 were cancer patients, so cancer has been recognized as a risk factor for COVID-19. Healthcare professionals have been under tremendous pressure to deliver services, and enrollment in research and clinical trials has decreased significantly. To put it simply, the pandemic has had a significant impact on cancer control efforts and was impacting the Cancer Profiling Market.