Gaucher Disease Treatment Market Size, Share, Opportunities, COVID-19 Impact, And Trends By Treatment Type (Enzyme Replacement Therapy (ERT), Substrate Reduction Therapy (SRT), Surgical Procedure), By Disease Type (Type I, Type II, Type III), By End-Users (Hospitals, Ambulatory Specialty Clinics, Clinical Research Institutes), And By Geography - Forecasts From 2022 To 2027

Published:  Apr 2022 Report Code: KSI061612288 Pages: 125

The Gaucher disease treatment market is projected to grow at a CAGR of 2.74% during the forecast period to reach US$1,223.955 million by 2027, from US$1012.952 million in 2020.

Gaucher disease is characterized by the build-up of glucocerebroside in cells and some organs, resulting in enlargement of the liver as well as the spleen. It is a genetic disease that shows symptoms such as fatigue, bruising, anaemia, and a low blood platelet count and is caused by a hereditary deficit of the enzyme glucocerebrosidase. Despite being the most common lysosomal storage disorder, Gaucher disease is a rare ailment with an incidence of 1 in 100,000 people.

One of the key reasons driving the Gaucher disease treatment market during the forecast period is the rising prevalence of Gaucher worldwide. Factors such as increasing Gaucher disease incidences and pharmaceutical companies' increased focus on developing innovative pharmaceuticals for treating Gaucher disease are likely to contribute to the market's growth significantly. Furthermore, rising concern for the growing incidences of Gaucher disease amongst people worldwide, combined with increasing government support and funding and rising per capita healthcare expenditure by several nations worldwide, are some of the factors expected to drive the growth of the global Gaucher disease market. According to the Centers for Medicare and Medicaid Services, healthcare spending in the United States increased by 4.6 percent in 2019 to US$ 3.8 trillion, or US$ 11,582 per person, accounting for 17.7 percent of GDP. Furthermore, the federal government accounted for 29.0 percent of total health expenditures, with families coming in second (28.4 percent). State and municipal governments accounted for 16.1 percent of overall healthcare expenditures, with other private sources accounting for the remaining 7.5 percent.

The market for Gaucher treatment may be limited by the high cost of treatment for the condition. Stringent government regulations governing the use of medications and therapies for the condition, as well as the high cost of enzyme replacement therapy and a lack of therapeutic options in poorer nations, may have an impact on market growth.

Key Developments

In 2021, the National Gaucher Foundation (NGF) started the Stepping Stones sustainer donating program. The long-term goal of this strategy is to provide a consistent source of funding for patient advocacy programs and provide financial assistance to the 6,000 persons in the United States who have Gaucher disease. Lysogene announced a research partnership with the Weizmann Institute of Science in July 2020 to produce a unique AAV gene therapy strategy for neuronopathic Gaucher's disease, Parkinson's disease, and other disorders caused by the GBA1 gene abnormalities. In 2020, Centogene and Evotec expanded their drug discovery collaboration focused on the protein target glucocerebrosidase, focusing on Gaucher's Disease. Gain Therapeutics, Inc. made a significant breakthrough in November 2021 in the potential to treat neurodegenerative disorders characterized by misfolded proteins, such as Alzheimer's Disease, Gaucher's Disease, and Parkinson's Disease.

By treatment type, the Gaucher disease treatment market is segmented into Enzyme Replacement Treatment type (ERT), Substrate Reduction Treatment (SRT), and surgical procedures. The ERT segment is expected to have a dominant market position owing to the rising global use of treating Gaucher disease and improved knowledge of the use of Enzyme Replacement Treatment.

By disease type, the Gaucher disease treatment market is segmented into Type I, Type II, and Type III. Due to the increasing number of patients suffering from type I Gaucher disease worldwide, type I Gaucher disease is seen to be the market's dominant category. Type I Gaucher affects around 95 percent of the population, making it the most common type of disease, according to the National Gaucher Foundation.

By end-users, the Gaucher disease treatment market is segmented into hospitals, ambulatory surgical centres, and clinical research institutes. Preference for hospitals is expected to fuel the segment’s growth due to the availability of innovative technology and many facilities available on a single site.

By geography, the Gaucher disease treatment market is segmented into five regions - North America, Europe, South America, the Middle East and Africa, and Asia Pacific regions. North America is expected to have the most significant market share in the Gaucher disease treatment market due to the increasing number of people suffering from the condition and expanding awareness of the utilization of effective treatment alternatives. The presence of prominent market players in the region, as well as their revenue-generating tactics, is also propelling the regional market forward. Because of increased awareness initiatives about Gaucher disease treatment, the European Gaucher disease treatment market is likely to remain the second-largest market.

COVID-19 Insights

The COVID-19 epidemic has resulted in various hurdles to medical care delivery, which vary based on a patient's underlying illness. Because of the pandemic, lockdown measures were implemented, prohibiting patient movement and identification, as well as severely overburdening healthcare institutions while raising concerns among patients. It will have a significant impact on the Gaucher disease treatment market. The COVID-19 outbreak would result in excessively long wait times for patients needing certain treatments.

Gaucher Disease Treatment Market Scope:

Report Metric Details
 Market size value in 2020  US$1012.952 million
 Market size value in 2027  US$1,223.955 million
 Growth Rate  CAGR of 2.74% from 2020 to 2027
 Base year  2020
 Forecast period  2022–2027
 Forecast Unit (Value)  USD Million
 Segments Covered  Treatment Type, Disease Type, End-Users, And Geography
 Regions covered  North America, South America, Europe, Middle East and Africa, Asia Pacific
 Companies covered  AVROBIO Inc., Gain Therapeutics, Inc., Pfizer Inc., Prevail Therapeutics, Sanofi,   Evotech, CANbridge Life Sciences Ltd., Lysogene, Orphazyme, Freeline
 Customization scope  Free report customization with purchase

 

Key Market Segments

  • By Treatment type
    • Enzyme Replacement Therapy (ERT)
    • Substrate Reduction Therapy (SRT)
    • Surgical Procedure
  • By Disease Type
    • type I
    • type II
    • type III
  • By End-Users
    • Hospitals
    • Ambulatory Specialty Clinics
    • Clinical Research Institutes
  • By Geography
    • North America
      • USA
      • Canada
      • Mexico
    • South America
      • Brazil
      • Argentina
      • Others
    • Europe
      • United Kingdom
      • Germany
      • France
      • Others
    • Middle East and Africa
      • Saudi Arabia
      • UAE
      • South Africa
      • Others
    • Asia Pacific
      • China
      • Japan
      • India
      • South Korea
      • Thailand
      • Indonesia
      • Taiwan
      • Others

Frequently Asked Questions (FAQs)

Q1. What will be the Gaucher disease treatment market size by 2027?
A1. The Gaucher disease treatment market is projected to reach a total market size of US$1,223.955 million by 2027. 


Q2. What are the growth prospects for the Gaucher disease treatment market?
A2. The global Gaucher disease treatment market is projected to grow at a CAGR of 2.74% during the forecast period. 


Q3. What is the size of the global Gaucher disease treatment market?
A3. Gaucher Disease Treatment Market was valued at US$1012.952 million in 2020. 


Q4. What factors are anticipated to drive Gaucher disease treatment market growth?
A4. One of the key reasons driving the Gaucher disease treatment market during the forecast period is the rising prevalence of Gaucher around the world.


Q5. Which region holds the largest market share in the Gaucher disease treatment market?
A5. North America is expected to have the largest share in the Gaucher disease treatment market due to the increasing number of people suffering from the condition and expanding awareness of the utilization of effective treatment alternatives.

1. INTRODUCTION
1.1. Market Definition
1.2. Market Segmentation


2. RESEARCH METHODOLOGY
2.1. Research Data
2.2. Assumptions


3. EXECUTIVE SUMMARY
3.1. Research Highlights


4. MARKET DYNAMICS
4.1. Market Drivers
4.2. Market Restraints
4.3. Porters Five Forces Analysis
4.3.1. Bargaining Power of Suppliers
4.3.2. Bargaining Powers of Buyers
4.3.3. Threat of Substitutes
4.3.4. The Threat of New Entrants
4.3.5. Competitive Rivalry in Industry
4.4. Industry Value Chain Analysis


5. GAUCHER DISEASE TREATMENT MARKET, BY TREATMENT TYPE 
5.1. Introduction
5.2. Enzyme Replacement Therapy (ERT)
5.3. Substrate Reduction Therapy (SRT)
5.4. Surgical Procedures


6. GAUCHER DISEASE TREATMENT MARKET, BY DISEASE TYPE
6.1. Introduction
6.2. Type I
6.3. Type II
6.4. Type III


7. GAUCHER DISEASE TREATMENT MARKET, BY END-USERS    
7.1. Introduction
7.2. Hospitals
7.3. Ambulatory Specialty Clinics 
7.4. Clinical Research Institutes


8. GAUCHER DISEASE TREATMENT MARKET, BY GEOGRAPHY
8.1. Introduction
8.2. North America
8.2.1. United States
8.2.2. Canada
8.2.3. Mexico
8.3. South America
8.3.1. Brazil
8.3.2. Argentina
8.3.3. Others
8.4. Europe
8.4.1. United Kingdom 
8.4.2. Germany
8.4.3. France
8.4.4. Others
8.5. Middle East and Africa
8.5.1. Saudi Arabia
8.5.2. UAE
8.5.3. South Africa
8.5.4. Others
8.6. Asia Pacific
8.6.1. China
8.6.2. Japan
8.6.3. India
8.6.4. South Korea
8.6.5. Thailand
8.6.6. Indonesia
8.6.7. Taiwan
8.6.8. Others


9. COMPETITIVE ENVIRONMENT AND ANALYSIS
9.1. Major Players and Strategy Analysis
9.2. Emerging Players and Market Lucrative
9.3. Mergers, Acquisition, Agreements, and Collaborations
9.4. Vendor Competitiveness Matrix


10. COMPANY PROFILES 
10.1. AVROBIO Inc.
10.2. Gain Therapeutics, Inc.
10.3. Pfizer Inc.
10.4. Prevail Therapeutics
10.5. Sanofi
10.6. Evotech
10.7. CANbridge Life Sciences Ltd.
10.8. Lysogene
10.9. Orphazyme
10.10. Freeline

AVROBIO Inc.

Gain Therapeutics, Inc.

Pfizer Inc.

Prevail Therapeutics

Sanofi

Evotech

CANbridge Life Sciences Ltd.

Lysogene

Orphazyme

Freeline

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