Global Biobetters Market Size, Share, Opportunities, And Trends By Type (Monoclonal Antibodies, Vaccines, Recombinant Proteins, Others), By Application (Oncology, Neurology, Nephrology, Orphan Indications, Others), By End-user (Biopharmaceuticals, Research Organisations) and Geography - Forecasts From 2025 To 2030

Description

Biobetters Market Size:

The Biobetters Market is anticipated to expand from USD 66.603 billion in 2025 to USD 97.907 billion in 2030, registering an 8.01% CAGR.

The low development cost of biobetters as compared to biologics will augment the market growth during the given forecast period. Biobetters are improved versions of originator biologics which are similar to existing biologics entities by action, potency, and other factors. Biobetters are formed as a result of chemical modification, protein fusion, altered amino acid sequence, or humanization of the glycosylation pattern, which aims for the same target as the original biological, but has its effect longer period of time, typically at lower doses and with fewer side effects. Biobetters differ from biosimilars in that they are not identical to the original product and have been designed to have some advantages. Biobetters are handled exactly as innovator molecules in the United States, and similar regulatory standards are expected elsewhere. They are new molecular entities and will be subject to the standards applied to all new drugs.

A biosimilar has no clinically meaningful differences in terms of safety and effectiveness from its reference product. In contrast, a biobetter can be thought of as an improved version of an existing biological product. There may be a change in structure that makes it safer or more effective or a change in the formulation that makes it easier to administer. A biobetter may have an easier clinical road since it benefits from prior knowledge of clinically effective targets/pathways. Biobetters allows companies to target an established mechanism, safety, and efficacy profile but gain the benefit of the patent protection and sales of a new molecular entity with significantly higher chances of successful registration.

The market is expected to show modest growth during the forecast period due to major manufacturers investing in the development of the biobetters in the face of impending biosimilar competition. The low development cost of biobetters as compared to the biologics will also augment the market growth during the given forecast period. Moreover, many blockbuster biologics are going off-patent by 2023, providing ample opportunities for the companies to develop biobetter, thus, positively impacting the market. However, lack of awareness among the patient population in regards to the betters will restrain the growth of the global biobetter market during the given forecast period.

Biobetters Market Segmentation Analysis:

By Type

By type, the global biobetter market is segmented as monoclonal antibodies, vaccines, recombinant proteins, and others. Monoclonal antibodies are expected to hold a significant share which may be attributed to the favorable regulatory policies, and high adoption rate of therapeutic antibodies in emerging economies.

By Geography

Geographically, the global biobetter market is segmented as North America, South America, Europe, the Middle East and Africa, and the Asia Pacific. Europe is expected to hold a significant share which may be attributed to the well-defined approval guidelines and the number of researches going in the region for biobetter development.

Segmentation

• By Type

  • Monoclonal Antibodies (mAbs)

  • Vaccines

  • Recombinant Proteins

  • Antibody–Drug Conjugates (ADCs)

  • Others

• By Application

  • Oncology

  • Neurology

  • Nephrology

  • Autoimmune & Inflammatory Diseases

  • Infectious Diseases

  • Others

• By End-User

  • Biopharmaceutical Companies

  • Contract Research Organizations (CROs)

  • Academic & Research Institutes

• By Geography

  • North America

    • USA

    • Canada

    • Mexico

  • South America

    • Brazil

    • Argentina

    • Others

  • Europe

    • United Kingdom

    • Germany

    • France

    • Spain

    • Others

  • Middle East and Africa

    • Saudi Arabia

    • UAE

    • Others

  • Asia Pacific

    • China

    • Japan

    • India

    • South Korea

    • Taiwan

    • Others

Table Of Contents

1. EXECUTIVE SUMMARY 

2. MARKET SNAPSHOT

2.1. Market Overview

2.2. Market Definition

2.3. Scope of the Study

2.4. Market Segmentation

3. BUSINESS LANDSCAPE 

3.1. Market Drivers

3.2. Market Restraints

3.3. Market Opportunities 

3.4. Porter’s Five Forces Analysis

3.5. Industry Value Chain Analysis

3.6. Policies and Regulations 

3.7. Strategic Recommendations 

4. TECHNOLOGICAL OUTLOOK

5. GLOBAL BIOBETTERS MARKET BY TYPE

5.1. Introduction

5.2. Monoclonal Antibodies (mAbs)

5.3. Vaccines

5.4. Recombinant Proteins

5.5. Antibody–Drug Conjugates (ADCs)

5.6. Others

6. GLOBAL BIOBETTERS MARKET BY APPLICATION

6.1. Introduction

6.2. Oncology

6.3. Neurology

6.4. Nephrology

6.5. Autoimmune & Inflammatory Diseases

6.6. Infectious Diseases

6.7. Others

7. GLOBAL BIOBETTERS MARKET BY END-USER

7.1. Introduction

7.2. Biopharmaceutical Companies

7.3. Contract Research Organizations (CROs)

7.4. Academic & Research Institutes

8. GLOBAL BIOBETTERS MARKET BY GEOGRAPHY

8.1. Introduction

8.2. North America

8.2.1. By Type

8.2.2. By Application

8.2.3. By End-User

8.2.4. By Country

8.2.4.1. USA

8.2.4.2. Canada

8.2.4.3. Mexico

8.3. South America

8.3.1. By Type

8.3.2. By Application

8.3.3. By End-User

8.3.4. By Country

8.3.4.1. Brazil

8.3.4.2. Argentina

8.3.4.3. Others

8.4. Europe

8.4.1. By Type

8.4.2. By Application

8.4.3. By End-User

8.4.4. By Country

8.4.4.1. United Kingdom

8.4.4.2. Germany

8.4.4.3. France

8.4.4.4. Spain

8.4.4.5. Others

8.5. Middle East and Africa

8.5.1. By Type

8.5.2. By Application

8.5.3. By End-User

8.5.4. By Country

8.5.4.1. Saudi Arabia

8.5.4.2. UAE

8.5.4.3. Others

8.6. Asia Pacific

8.6.1. By Type

8.6.2. By Application

8.6.3. By End-User

8.6.4. By Country

8.6.4.1. China

8.6.4.2. Japan

8.6.4.3. India

8.6.4.4. South Korea

8.6.4.5. Taiwan

8.6.4.6. Others

9. COMPETITIVE ENVIRONMENT AND ANALYSIS

9.1. Major Players and Strategy Analysis

9.2. Market Share Analysis

9.3. Mergers, Acquisitions, Agreements, and Collaborations

9.4. Competitive Dashboard

10. COMPANY PROFILES

10.1. Celltrion

10.2. GC Pharma

10.3. Ildong Pharmaceutical Co., Ltd.

10.4. Samsung Bioepis

10.5. Amgen Inc.

10.6. Novartis AG

10.7. Galil-Ofek

11. APPENDIX

11.1. Currency

11.2. Assumptions

11.3. Base and Forecast Years Timeline

11.4. Key benefits for the stakeholders

11.5. Research Methodology 

11.6. Abbreviations 

LIST OF FIGURES

LIST OF TABLES

Companies Profiled

Celltrion

GC Pharma

Ildong Pharmaceutical Co., Ltd.

Samsung Bioepis

Amgen Inc.

Novartis AG

Galil-Ofek

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