Preparative Chromatography Market Size, Share, Opportunities, And Trends By Product (Systems, Resins, Detectors, Consumables, Columns), By Application (Pharmaceuticals, Cosmetics, Food Ingredients, Molecular Biology And Diagnostics, Fine Chemical And Synthetic Chemistry, Environmental Chemistry, Forensic Sciences, Drugs Of Abuse And Sports Drug Testing, Others), By End-user (Pharmaceutical And Biotechnology Companies, Contract Research Organizations, Food And Beverage Industry, Chemical Industry, Diagnostic Laboratories, Reference Laboratories, National Anti-doping Organizations, Academic And Research Institutes), And By Geography - Forecasts From 2024 To 2029

  • Published : Mar 2024
  • Report Code : KSI061616739
  • Pages : 149

The preparative chromatography market is expected to witness significant growth during the forecasted period.

Within the larger chromatography sector, the preparative chromatography market is a subset dedicated to the larger-scale separation and purification of target molecules from complicated mixtures. It includes a range of methods, including supercritical fluid chromatography (SFC), gas chromatography (GC), and liquid chromatography (LC). Pharmaceuticals, biotechnology, food and beverage, and environmental analysis are just a few of the industries this market serves. Important motivators include the requirement for effective purification procedures, strict laws controlling drug development and manufacture, and the growing demand for high-purity products in biotechnology and pharmaceuticals.

The market is expanding due to developments in chromatography technologies, including automated systems and unique stationary phases. The future of preparative chromatography is also being shaped by the growing trend toward green chromatography and the development of sustainable methods. The market is distinguished by immense competition and rapid innovation.

Market Drivers:

  • Increasing demand in pharmaceutical and biotechnology industries is anticipated to boost the preparative chromatography market.

The market for preparative chromatography is supported by the growing demand from the biotechnology and pharmaceutical industries. Isolating and purifying target components such as proteins, peptides, and active pharmaceutical ingredients (APIs) is becoming more and more important as drug discovery, biopharmaceutical production, and personalized medicine progress. Technological advances in chromatography improve productivity and scalability, yet strict regulations require thorough purification procedures to ensure product quality and compliance. Rises in automation use are attributed to reproducibility and streamlined operations.

Additionally, the growing biopharmaceutical pipeline demands preparative chromatography equipment that can purify complex biomolecules on a large scale, reaffirming the technique's critical position in the expansion of these industries.

In 2021, a leading global partner of the biopharmaceutical sector, Sartorius Stedim Biotech, announced that it had reached a deal to buy Novasep's chromatography process equipment segment. The parties decided that until the required regulatory permits were secured, they would not reveal the purchase price. The division of Novasep anticipates double-digit profit margins and sales revenue of about 37 million euros in 2020. The division employs about 100 individuals, most of whom are based at the Pompey site in northern France and a small number of whom are also employed in the USA, China, and India.

  • Advancements in technology are expected to drive the preparative chromatography market.

The preparative chromatography market is being driven by technological advancements in chromatography, such as high-resolution detection systems, sophisticated stationary phases, and innovative column designs. By improving separation efficiency, resolution, and scalability, these developments allow for increased target chemical purity and better throughput. In addition, the creation of automated systems optimizes processes, guaranteeing consistency and reducing the need for human involvement. Preparative chromatography is increasingly being used for the isolation and purification of complex chemicals on a commercial scale as a result of technological advancements that meet the growing need for effective purification solutions in biotechnology, pharmaceutical, and other industries.

In May 2021, The WatersTM ArcTM Premier System was unveiled by Waters Corporation. It is the first liquid chromatography system designed with Waters' innovative MaxPeakTM High-Performance Surface (HPS) technology and tailored for chromatographic separations on 2.5–3.5micron columns. By virtually eliminating surface interactions between sample analytes and instrument and column hardware, the new system enhances Waters’ best-selling MaxPeak Premier Columns. This reduces laboratory time wasted on expensive passivation and increases confidence in separation results.

  • Increasing adoption of automated systems to boost the preparative chromatography market.

The growing utilization of automated solutions, which may improve reproducibility, reduce manual interventions, and streamline workflows, is driving the preparative chromatography market. Because automated systems may increase throughput, improve process control, and save personnel costs, they are an essential tool for biotechnology, pharmaceutical, and other businesses that need to purify materials efficiently. Automated preparative chromatography systems are well-positioned to address the growing demand for the fast and dependable isolation of target chemicals. This will drive market expansion and support a broad range of applications across several industries.

In October 2021, The ProdigyTM Preparative High-Performance Liquid Chromatography (HPLC) system was recently released by CEM Corporation. The system's distinctive raised temperature capacity, which outperforms conventional preparative HPLC in terms of resolution and separation capabilities, is essential. The Prodigy was created to enhance biomolecule purification, particularly for synthetic peptides, which frequently encounter challenges in their purification process because of minute variations in their artificial contaminants. With column diameters as large as 50 mm, the Prodigy can be used to load more than 1 gram of peptide each injection.

Asia Pacific region is expected to grow significantly.

Rising demand for high-purity chemicals, growing research and development efforts, and the rise of the pharmaceutical and biotechnology industries are all contributing to the preparative chromatography market growth in Asia-Pacific. Adoption is being fueled by developments in chromatographic technologies as well as regulatory compliance needs. Automation is increasing productivity and lowering environmental impact when combined with an emphasis on sustainability and green chemistry. The region's developing biopharmaceutical pipeline and new applications in sectors like food and beverage processing also aid in the market's growth. In general, preparative chromatography suppliers have a lot of prospects in Asia-Pacific, as the market is expected to continue rising gradually.

In December 2023, to accelerate technology adoption, innovation, digital transformation, and business efficiencies through a concentrated hub of talent that will work across the Waters worldwide enterprise, Waters Corporation opened its new worldwide Capability Center (GCC). Situated in the recently constructed RMZ Ecoworld technology park in Bengaluru, the Waters India GCC is a WELL and LEED Platinum-certified campus that epitomizes dedication to a healthy and environmentally responsible office.

Market Restraints

  • Continuous improvement in scalability and cost-effectiveness can constrain the market for preparative chromatography.

One major challenge in the preparative chromatography market is the need for continuous improvement in scalability and cost-effectiveness. While chromatography techniques are highly efficient for small-scale purification, challenges arise when scaling up to industrial levels due to limitations in column packing, resin stability, and process economics. Overcoming these challenges requires innovative approaches to enhance throughput, reduce operating costs, and optimize process integration, ensuring that preparative chromatography remains viable for large-scale production across various industries.

Market Developments:

  • October 2023- Tecan introduced Resolvex Prep, a state-of-the-art benchtop automation solution for sample preparation in chromatography.
  • June 2023- A leading global provider of scientific services, Thermo Fisher Scientific Inc., has successfully acquired MarqMetrix, a privately held company that develops Raman-based spectroscopic systems for in-line measurement. MarqMetrix offers customers a simplified method to make precise and accurate measurements throughout the manufacturing process for a wide range of applications, including biopharma and pharmaceuticals, oil and gas, chemicals, and polymers. MarqMetrix offers innovative and fit-for-purpose in-line Process Analytical Technology (PAT).

Market Segmentation:

  • By Product:
    • Systems
    • Resins
    • Detectors
    • Consumables
    • Columns
  • By Application:
    • Pharmaceuticals
    • Cosmetics
    • Food Ingredients
    • Molecular Biology and Diagnostics
    • Fine Chemical and Synthetic Chemistry
    • Environmental Chemistry
    • Forensic Sciences
    • Drugs of Abuse and Sports Drug Testing
    • Others
  • By End-user:
    • Pharmaceutical and Biotechnology Companies
    • Contract Research Organizations
    • Food and Beverage Industry
    • Chemical Industry
    • Diagnostic Laboratories
    • Reference Laboratories
    • National Anti-doping Organizations
    • Academic and Research Institutes
  • By Geography:
    • North America
      • United States
      • Canada
      • Mexico
    • South America
      • Brazil
      • Argentina
      • Others
    • Europe
      • United Kingdom
      • Germany
      • France
      • Italy
      • Spain
      • Others
    • Middle East and Africa
      • Saudi Arabia
      • UAE
      • Others
    • Asia Pacific
      • Japan
      • China
      • India
      • South Korea
      • Taiwan
      • Thailand
      • Indonesia
      • Others

1. INTRODUCTION

1.1. Market Overview

1.2. Market Definition

1.3. Scope of the Study

1.4. Market Segmentation

1.5. Currency

1.6. Assumptions

1.7. Base, and Forecast Years Timeline

1.8. Key Benefits for the Stakeholder

2. RESEARCH METHODOLOGY  

2.1. Research Design

2.2. Research Processes

3. EXECUTIVE SUMMARY

3.1. Key Findings

3.2. Analyst View

4. MARKET DYNAMICS

4.1. Market Drivers

4.2. Market Restraints

4.3. Porter’s Five Forces Analysis

4.3.1. Bargaining Power of Suppliers

4.3.2. Bargaining Power of Buyers

4.3.3. Threat of New Entrants

4.3.4. Threat of Substitutes

4.3.5. Competitive Rivalry in the Industry

4.4. Industry Value Chain Analysis

4.5. Analyst View

5. PREPARATIVE CHROMATOGRAPHY MARKET BY PRODUCT

5.1. Introduction

5.2. Systems

5.2.1. Market Trends and Opportunities

5.2.2. Growth Prospects

5.2.3. Semi-preparative HPLC Systems

5.2.4. Preparative HPLC Systems

5.3. Resins

5.3.1. Market Trends and Opportunities

5.3.2. Growth Prospects

5.3.3. Affinity Chromatography (AC)

5.3.4. Ion exchange Chromatography (IEX)

5.3.5. Size-exclusion Resins

5.3.6. Hydrophobic Interaction Resins

5.3.7. Mixed-mode/Multi-mode Resins

5.3.8. Other Resins

5.4. Detectors

5.4.1. Market Trends and Opportunities

5.4.2. Growth Prospects

5.4.3. UV/Vis Detectors

5.4.4. Diode-array Detectors

5.4.5. Refractive Index Detectors

5.4.6. Fluorescence Detectors

5.4.7. Mass Spectrometry Detectors

5.4.8. Evaporating Light Scattering Detectors

5.4.9. Electrochemical Detectors

5.5. Consumables

5.5.1. Market Trends and Opportunities

5.5.2. Growth Prospects

5.6. Columns

5.6.1. Market Trends and Opportunities

5.6.2. Growth Prospects

5.6.3. Prepacked Columns

5.6.4. Empty Columns

6. PREPARATIVE CHROMATOGRAPHY MARKET BY APPLICATION

6.1. Introduction

6.2. Pharmaceuticals

6.2.1. Market Trends and Opportunities

6.2.2. Growth Prospects

6.3. Cosmetics

6.3.1. Market Trends and Opportunities

6.3.2. Growth Prospects

6.4. Food Ingredients

6.4.1. Market Trends and Opportunities

6.4.2. Growth Prospects

6.5. Molecular Biology and Diagnostics

6.5.1. Market Trends and Opportunities

6.5.2. Growth Prospects

6.6. Fine Chemical and Synthetic Chemistry

6.6.1. Market Trends and Opportunities

6.6.2. Growth Prospects

6.7. Environmental Chemistry

6.7.1. Market Trends and Opportunities

6.7.2. Growth Prospects

6.8. Forensic Sciences

6.8.1. Market Trends and Opportunities

6.8.2. Growth Prospects

6.9. Drugs of Abuse and Sports Drug Testing

6.9.1. Market Trends and Opportunities

6.9.2. Growth Prospects

6.10. Others

6.10.1. Market Trends and Opportunities

6.10.2. Growth Prospects

7. PREPARATIVE CHROMATOGRAPHY MARKET BY END-USER

7.1. Introduction

7.2. Pharmaceutical and Biotechnology Companies

7.2.1. Market Trends and Opportunities

7.2.2. Growth Prospects

7.3. Contract Research Organizations

7.3.1. Market Trends and Opportunities

7.3.2. Growth Prospects

7.4. Food and Beverage Industry

7.4.1. Market Trends and Opportunities

7.4.2. Growth Prospects

7.5. Chemical Industry

7.5.1. Market Trends and Opportunities

7.5.2. Growth Prospects

7.6. Diagnostic Laboratories

7.6.1. Market Trends and Opportunities

7.6.2. Growth Prospects

7.7. Reference Laboratories

7.7.1. Market Trends and Opportunities

7.7.2. Growth Prospects

7.8. National Anti-doping Organizations

7.8.1. Market Trends and Opportunities

7.8.2. Growth Prospects

7.9. Academic and Research Institutes

7.9.1. Market Trends and Opportunities

7.9.2. Growth Prospects

8. PREPARATIVE CHROMATOGRAPHY MARKET BY GEOGRAPHY

8.1. Introduction

8.2. North America

8.2.1. By Product

8.2.2. By Application

8.2.3. By End User

8.2.4. By Country

8.2.4.1. United States

8.2.4.1.1. Market Trends and Opportunities

8.2.4.1.2. Growth Prospects

8.2.4.2. Canada

8.2.4.2.1. Market Trends and Opportunities

8.2.4.2.2. Growth Prospects

8.2.4.3. Mexico

8.2.4.3.1. Market Trends and Opportunities

8.2.4.3.2. Growth Prospects

8.3. South America

8.3.1. By Product

8.3.2. By Application

8.3.3. By End User

8.3.4. By Country 

8.3.4.1. Brazil

8.3.4.1.1. Market Trends and Opportunities

8.3.4.1.2. Growth Prospects

8.3.4.2. Argentina

8.3.4.2.1. Market Trends and Opportunities

8.3.4.2.2. Growth Prospects

8.3.4.3. Others

8.3.4.3.1. Market Trends and Opportunities

8.3.4.3.2. Growth Prospects

8.4. Europe

8.4.1. By Product

8.4.2. By Application

8.4.3. By End User

8.4.4. By Country

8.4.4.1. United Kingdom

8.4.4.1.1. Market Trends and Opportunities

8.4.4.1.2. Growth Prospects

8.4.4.2. Germany

8.4.4.2.1. Market Trends and Opportunities

8.4.4.2.2. Growth Prospects

8.4.4.3. France

8.4.4.3.1. Market Trends and Opportunities

8.4.4.3.2. Growth Prospects

8.4.4.4. Italy

8.4.4.4.1. Market Trends and Opportunities

8.4.4.4.2. Growth Prospects

8.4.4.5. Spain

8.4.4.5.1. Market Trends and Opportunities

8.4.4.5.2. Growth Prospects

8.4.4.6. Others

8.4.4.6.1. Market Trends and Opportunities

8.4.4.6.2. Growth Prospects

8.5. Middle East and Africa

8.5.1. By Product

8.5.2. By Application

8.5.3. By End User

8.5.4. By Country

8.5.4.1. Saudi Arabia

8.5.4.1.1. Market Trends and Opportunities

8.5.4.1.2. Growth Prospects

8.5.4.2. UAE

8.5.4.2.1. Market Trends and Opportunities

8.5.4.2.2. Growth Prospects

8.5.4.3. Others

8.5.4.3.1. Market Trends and Opportunities

8.5.4.3.2. Growth Prospects

8.6. Asia Pacific

8.6.1. By Product

8.6.2. By Application

8.6.3. By End User

8.6.4. By Country

8.6.4.1. Japan

8.6.4.1.1. Market Trends and Opportunities

8.6.4.1.2. Growth Prospects

8.6.4.2. China

8.6.4.2.1. Market Trends and Opportunities

8.6.4.2.2. Growth Prospects

8.6.4.3. India

8.6.4.3.1. Market Trends and Opportunities

8.6.4.3.2. Growth Prospects

8.6.4.4. South Korea

8.6.4.4.1. Market Trends and Opportunities

8.6.4.4.2. Growth Prospects

8.6.4.5. Taiwan

8.6.4.5.1. Market Trends and Opportunities

8.6.4.5.2. Growth Prospects

8.6.4.6. Thailand

8.6.4.6.1. Market Trends and Opportunities

8.6.4.6.2. Growth Prospects

8.6.4.7. Indonesia

8.6.4.7.1. Market Trends and Opportunities

8.6.4.7.2. Growth Prospects

8.6.4.8. Others

8.6.4.8.1. Market Trends and Opportunities

8.6.4.8.2. Growth Prospects

9. COMPETITIVE ENVIRONMENT AND ANALYSIS

9.1. Major Players and Strategy Analysis

9.2. Market Share Analysis

9.3. Mergers, Acquisitions, Agreements, and Collaborations

9.4. Competitive Dashboard

10. COMPANY PROFILES

10.1. Thermo Fisher Scientific Inc.

10.2. Bio-Rad Laboratories, Inc.

10.3. Agilent Technologies, Inc.

10.4. Waters Corporation

10.5. Cytiva (Danaher)

10.6. Sartorius AG

10.7. Shimadzu Corporation

10.8. PerkinElmer Inc.

10.9. Hitachi High-Tech Corporation

10.10. KNAUER Wissenschaftliche Geräte GmbH


Thermo Fisher Scientific Inc.

Bio-Rad Laboratories, Inc.

Agilent Technologies, Inc.

Waters Corporation

Cytiva (Danaher)

Sartorius AG

Shimadzu Corporation

PerkinElmer Inc.

Hitachi High-Tech Corporation

KNAUER Wissenschaftliche Geräte GmbH