Scaffold Technology Market Size, Share, Opportunities, And Trends By Type (Hydrogels, Polymeric Scaffolds, Micropatterned Surface Microplates, Nanofiber Based Scaffolds), By Disease (Orthopedics, Musculoskeletal, & Spine, Cancer, Skin & Integumentary, Dental, Cardiology & Vascular, Neurology, Urology, GI, Gynecology, Others), By Application (Stem Cell Therapy, Regenerative Medicine, & Tissue Engineering, Drug Discovery, Others), By End-Use (Biotechnology & Pharmaceutical Organizations, Research Laboratories & Institutes, Hospitals & Diagnostic Centers, Others), And By Geography - Forecasts From 2023 To 2028

  • Published : Jul 2023
  • Report Code : KSI061615761
  • Pages : 152

The global scaffold technology market is estimated to grow at a CAGR of 13.57% during the forecast period.

The field of scaffold technology falls under tissue engineering. A scaffold is an extracellular substance that offers mechanical, chemical, and biological support. When the new tissue is forming, the substance serves as a template. Cells and scaffolds are the main elements of engineered tissues. Scaffolds give structural support to cells, which then allows for the formation of new tissues.

Growth drivers for the scaffold technology market

The increased need for 3D cellular models for use in biological research and translational studies is the growth driver for the scaffold technology market. The scaffold technology market share is expanding as the 3D cell culture is rising due to difficulties in drug development process. The study of virology and epidemiology, the creation of in vitro model systems, and the search for effective anti-infective therapies all make substantial use of tissue engineering fueling the scaffold technology market growth.

Rising application in 3D cell cultures

For 3D cell culture, scaffolds can be useful support. Scaffolds enable the movement of oxygen, nutrients, and waste because of their porosity. Cells can therefore multiply and move around the scaffold web before adhering to it. The maturing cells interact with one another as they grow and eventually transform into structures that are connected to the tissues from which they originally came. Spheroids, a type of cell structure commonly used for drug screening and other 3D cell culture applications, are the most common form of presentation for these aggregates. This growing application of scaffolding in 3D cell culture is expected to fuel the scaffold technology market growth.

Technological advancements in scaffold technology

As tissue engineering advances, scientists are working hard to develop new methods for creating more sophisticated scaffolds from biocompatible polymers with improved porosity, suitable mechanical strength, and a variety of shapes and sizes for potential applications in the biomedical field generally and tissue engineering specifically. These advancements are major growth drivers for the scaffold technology market. Solvent casting, solution blow spinning, particle leaching, self-assembly, gas foaming, fiber mesh, and lithography are some of the processes included and are working as major growth drivers for the scaffold technology market.

Increasing use in the treatment of cancer

To create a variety of 3D scaffolds to treat cancer recurrence, several biocompatible polymers that have received FDA approval have been established which is leading to the scaffold technology market growth. For choosing a polymer, the type of tumour microenvironment, metastasis, chemo medicines and immunotherapeutics are analyzed because of various qualities such as high surface volume, high porosity and tunable mechanical properties. 3D scaffolds are of interest for cancer immunotherapy and are further upsurging the scaffold technology market share.

Nano-fiber scaffold is predicted to hold a significant market share

Nano-fiber scaffold utilization is expanding due to its growing use in tissue engineering and regeneration applications. The uses of these scaffolds for tissue engineering are also being expanded by researchers. For instance, scientists around the globe are focusing on research related to nanofiber scaffold usage in the creation of nerve tissue. Nano-sized structures that can serve as an extracellular matrix for cellular transformation are made using techniques like electrospinning. Additionally, electrospinning provides several benefits like simplicity of use, affordability, and high flexibility, which can accelerate the scaffold technology market growth.

Government initiatives to fuel the market

The scaffold technology market is expanding due to government initiatives throughout the world. For instance, in June 2023, the Indian Drugs Controller gave their permission to the first locally created tissue engineering scaffold made from mammalian organs, a Class D biomedical device that may quickly and affordably treat skin lesions with little scarring. The Department of Science and Technology (DST) and Sree Chira Triunal Institute for Medical Sciences and Technology, collaborated to meet all the legal requirements to form the Central Drugs Standard Control Organization, Government of India.

North America is predicted to hold the maximum market share in the scaffold technology market

The scaffold technology market is anticipated to be more prevalent in North America. This can be attributed to a rise in research on stem cells and regenerative medicine, increased funding for expanding the applications of these technologies, and a well-established healthcare system. Researchers improved 3D micro scaffold technology, which helps reprogrammed neural stem cells and supports connections between neurons. Instead of injecting individual cells, these networks exhibited greater brain survival in mice. Also, in recent work supported by the National Institute of Biomedical Imaging and Bioengineering, stem cell biologists and biomaterial specialists collaborated.

Major market players focus on product innovation

For tissue regeneration, many businesses are creating novel 3D bio-printed customized scaffolds. For instance, 3D Systems and United Therapeutics Corporation collaborated to create cutting-edge 3D-printed organ technology in June 2022. Nanofiber scaffolds are gaining popularity because of their high surface area-to-volume ratio and capacity to replicate the fibrous structure of the extracellular matrix in nature. Additionally, in November 2022, Gelomics and Rousselot announced a cobranding partnership that calls for the usage of Gelomics' LunaGel 3D Tissue Culture System and Rousselot Biomedical's X-Pure GelMA (gelatin methacryloyl) extracellular matrix.

Market Key Developments

  • In June 2023, The National Institutes of Health (NIH) awarded RevBio, Inc. a USD 2 million grant for the creation of their innovative dental adhesive bone scaffold product.
  • In April 2023, to produce hydrogel scaffolds and conduct research and development for organ-on-a-chip technology to improve drug discovery and development, Systemic Bio constructed a new lab in Texas, the United States.
  • In August 2022, Conmed announced the acquisition of Biorez, a provider of bio-inductive scaffolds, to increase its selection of soft tissue healing products for use in sports medicine.


  • By Type
    • Hydrogels
    • Polymeric Scaffolds
    • Micropatterned Surface Microplates
    • Nanofiber Based Scaffolds
  • By Disease
    • Orthopedics, Musculoskeletal, & Spine
    • Cancer
    • Skin & Integumentary
    • Dental
    • Cardiology & Vascular
    • Neurology
    • Urology
    • GI, Gynecology
    • Others
  • By Application
    • Stem Cell Therapy, Regenerative Medicine, & Tissue Engineering
    • Drug Discovery
    • Others
  • By End-Use
    • Biotechnology & Pharmaceutical Organizations
    • Research Laboratories & Institutes
    • Hospitals & Diagnostic Centers
    • Others
  • By Geography
    • North America
      • United States
      • Canada
      • Mexico
    • South America
      • Brazil
      • Argentina
      • Others
    • Europe
      • United Kingdom
      • Germany
      • France
      • Spain
      • Others
    • Middle East and Africa
      • Saudi Arabia
      • UAE
      • Israel
      • Others
    • Asia Pacific
      • Japan
      • China
      • India
      • South Korea
      • Indonesia
      • Thailand
      • Others

Frequently Asked Questions (FAQs)

The scaffold technology market is estimated to grow at a CAGR of 13.57% during the forecast period.
Prominent key market players in the scaffold technology market include Thermo Fisher Scientific, Inc., Merck KGaA, REPROCELL Inc., 3D Biotek LLC, and Becton, Dickinson, and Company, among others.
The global scaffold technology market has been segmented by type, disease, application, end-use, and geography.
The increased need for 3D cellular models for use in biological research and translational studies is the growth driver for the scaffold technology market.
North America is predicted to hold the maximum share of the scaffold technology market.


1.1. Market Overview

1.2. Market Definition

1.3. Scope of the Study

1.4. Market Segmentation

1.5. Currency

1.6. Assumptions

1.7. Base, and Forecast Years Timeline


2.1. Research Data

2.2. Assumptions


3.1. Research Highlights


4.1. Market Drivers

4.2. Market Restraints

4.3. Porter’s Five Force Analysis

4.3.1. Bargaining Power of Suppliers

4.3.2. Bargaining Power of Buyers

4.3.3. Threat of New Entrants

4.3.4. Threat of Substitutes

4.3.5. Competitive Rivalry in the Industry

4.4. Industry Value Chain Analysis


5.1. Introduction

5.2. Hydrogels

5.3. Polymeric Scaffolds

5.4. Micropatterned Surface Microplates

5.5. Nanofiber Based Scaffolds


6.1. Introduction

6.2. Orthopedics, Musculoskeletal, & Spine

6.3. Cancer

6.4. Skin & Integumentary

6.5. Dental

6.6. Cardiology & Vascular

6.7. Neurology

6.8. Urology

6.9. GI, Gynecology

6.10. Others


7.1. Introduction

7.2. Stem Cell Therapy, Regenerative Medicine, & Tissue Engineering

7.3. Drug Discovery

7.4. Others


8.1. Introduction

8.2. Biotechnology & Pharmaceutical Organizations

8.3. Research Laboratories & Institutes

8.4. Hospitals & Diagnostic Centers

8.5. Others


9.1. Introduction

9.2. North America

9.2.1. United States

9.2.2. Canada

9.2.3. Mexico

9.3. South America

9.3.1. Brazil

9.3.2. Argentina

9.3.3. Others

9.4. Europe

9.4.1. United Kingdom

9.4.2. Germany

9.4.3. France

9.4.4. Spain

9.4.5. Others

9.5. The Middle East and Africa

9.5.1. Saudi Arabia

9.5.2. UAE

9.5.3. Israel

9.5.4. Others

9.6. Asia Pacific

9.6.1. Japan

9.6.2. China

9.6.3. India

9.6.4. South Korea

9.6.5. Indonesia

9.6.6. Thailand

9.6.7. Others


10.1. Major Players and Strategy Analysis

10.2. Emerging Players and Market Lucrativeness

10.3. Mergers, Acquisitions, Agreements, and Collaborations

10.4. Vendor Competitiveness Matrix


11.1. Thermo Fisher Scientific, Inc.

11.2. Merck KGaA

11.3. REPROCELL Inc.

11.4. 3D Biotek LLC

11.5. Becton, Dickinson, and Company

11.6. Medtronic

11.7. Matricel GmbH

11.8. Akron Biotech

11.9. Avacta Life Sciences Limited.

11.10. Vericel Corporation

Thermo Fisher Scientific, Inc.

Merck KGaA


3D Biotek LLC

Becton, Dickinson, and Company


Matricel GmbH

Akron Biotech

Avacta Life Sciences Limited.

Vericel Corporation