US Probiotics-Based Cleaning Supplies Market Size, Share, Opportunities, And Trends By Organic Source (Lactobacillus, Other Bacillus Strains), By Form (Powder, Liquid, Others), And By End-User (Household, Hospitals, Food and Beverages, Others) - Forecasts From 2025 To 2030

US Probiotics-Based Cleaning Supplies Market Size:

The US probiotics-based cleaning supplies market is projected to grow at a significant CAGR during the forecast period.

US Probiotics-Based Cleaning Supplies Market Highlights

• Bacillus strains dominate due to stability, enzyme production, and efficacy in diverse cleaning applications.
• Liquid probiotic cleaners lead for convenience, precise dosing, and compatibility with household, commercial use.
• Health concerns favor probiotic cleaners, reducing chemical exposure for families and allergy sufferers.
• Technological advancements in microbial stabilization enhance the shelf life and performance of probiotic cleaners.

Introduction to the US Probiotics-Based Cleaning Supplies Market:

The US probiotics-based cleaning supplies market represents an innovative segment within the broader household cleaning industry, leveraging beneficial microorganisms to offer sustainable and health-conscious cleaning solutions. These products utilize probiotic bacteria, such as Bacillus species, to break down organic matter, neutralize odors, and reduce harmful pathogens on surfaces. Unlike traditional chemical-based cleaners, probiotic cleaners promote a balanced microbial environment, aligning with growing consumer demand for eco-friendly and non-toxic alternatives. This market is gaining traction among environmentally conscious consumers, commercial facilities, and industries prioritizing sustainability, driven by advancements in biotechnology and shifting regulatory landscapes.

Probiotic cleaning supplies are formulated to introduce live beneficial bacteria into cleaning processes, which continue to work on surfaces post-application, outcompeting harmful bacteria and reducing the need for frequent reapplication. Products range from household surface cleaners and laundry detergents to specialized solutions for healthcare and hospitality sectors. The market is part of the larger bio-based cleaning products sector, which is experiencing robust growth due to consumer awareness of environmental and health impacts. The US probiotic cleaning segment is poised for growth, supported by innovations in microbial formulations and delivery systems.

Recent developments underscore the market’s potential. Partnerships between biotech firms and cleaning product manufacturers are also accelerating product innovation, with companies like Novozymes expanding their microbial solutions for cleaning applications.

US Probiotics-Based Cleaning Supplies Market Drivers:

• Consumer Demand for Sustainability

Growing environmental consciousness is a primary driver, with consumers increasingly seeking biodegradable and eco-friendly cleaning solutions to reduce chemical runoff and plastic waste. Probiotic cleaners, leveraging naturally occurring bacteria to clean surfaces, align with this trend by minimizing environmental impact. According to McKinsey, approximately 60% of US consumers prioritize sustainable packaging and products, a trend extending to cleaning supplies. Additionally, businesses are adopting green certifications to meet corporate sustainability goals, boosting demand for probiotic-based products in commercial settings like hotels and offices.

• Health and Safety Concerns

Post-pandemic awareness of hygiene has intensified focus on non-toxic cleaning alternatives that reduce health risks, such as respiratory issues and skin irritations. Probiotic cleaners, which use beneficial bacteria to outcompete pathogens, offer a safer option for households, particularly those with children, pets, or allergy sufferers. Azelis reported in 2024 that probiotic cleaning solutions are gaining traction in healthcare and residential markets due to their low toxicity and allergen-friendly profiles. This trend is further supported by consumer preference for products free from volatile organic compounds (VOCs), which traditional cleaners often contain.

• Regulatory Support

Regulatory frameworks in the US are increasingly favoring environment-friendly products, providing a tailwind for probiotic cleaners. The Environmental Protection Agency (EPA) encourages low-VOC and biodegradable formulations through programs like the Safer Choice label, which some probiotic products qualify for. State-level initiatives, such as New York’s push for greener cleaning practices in public facilities, further incentivize adoption. These regulations align with global sustainability standards, easing market entry for manufacturers of probiotic-based solutions and fostering trust among eco-conscious consumers.

• Technological Advancements

Advances in biotechnology, particularly in microbial stabilization and delivery systems, have improved the efficacy and shelf life of probiotic cleaners, making them competitive with chemical-based alternatives. Innovations such as microencapsulation protect probiotic bacteria during storage, ensuring consistent performance on surfaces. In 2025, Unilever launched Cif Infinite Clean spray, which incorporates probiotics, demonstrating the commercial application of these advancements, with claims of prolonged cleaning efficacy. Collaborations between biotech firms and cleaning product manufacturers, such as Novozymes’ microbial solutions, are accelerating product development.

US Probiotics-Based Cleaning Supplies Market Restraints:

• Limited Consumer Awareness

Despite growing interest, many US consumers lack understanding of how probiotic cleaners function, leading to skepticism about their effectiveness compared to familiar chemical-based products. This knowledge gap hinders adoption, particularly among price-sensitive demographics. Without widespread awareness, the market struggles to convert curious consumers into loyal users.

• Higher Production Costs

Developing stable, high-quality probiotic formulations involves significant costs, including sourcing specific bacterial strains, ensuring viability during storage, and meeting safety standards. These expenses translate to premium pricing, which can deter budget-conscious consumers. An industry article from Azelis highlighted that production complexities, such as maintaining microbial stability, increase costs compared to traditional cleaners. This price barrier limits market penetration, particularly in mass-market retail channels.

• Regulatory Hurdles

While regulations support eco-friendly products, probiotic cleaners face stringent scrutiny due to their microbial content. The EPA and other bodies require extensive safety and efficacy data to ensure these products pose no health risks, which can delay approvals and raise compliance costs. A 2023 Senate bill discussion on green cleaning emphasized the need for rigorous testing of bio-based products, underscoring regulatory complexity. These hurdles can slow innovation and market entry for smaller manufacturers.

US Probiotics-Based Cleaning Supplies Market Segmentation Analysis:

• Bacillus Strains are expected to lead the market expansion

Probiotic cleaning products rely on specific microbial strains, primarily Lactobacillus and Bacillus species, to deliver cleaning efficacy through microbial activity. These organic sources degrade organic matter, neutralize odors, and reduce pathogens. Bacillus strains dominate due to their robustness and versatility in various cleaning applications.

Bacillus strains, such as Bacillus subtilis and Bacillus coagulans, are the leading organic source in the US probiotics-based cleaning supplies market due to their stability, enzyme production, and effectiveness in diverse environments. These strains produce extracellular enzymes like proteases and lipases, which break down organic residues, making them ideal for cleaning surfaces, textiles, and drains. Their spore-forming nature ensures a longer shelf life and resilience in harsh conditions, unlike more delicate Lactobacillus strains. A 2023 study published in Microorganisms highlighted that Bacillus-based probiotic cleaners significantly reduce dry biofilms on hospital surfaces, demonstrating their efficacy in high-stakes environments. Additionally, Bacillus strains are favored in commercial applications, such as hospitality and food processing, due to their ability to maintain activity on surfaces post-application, providing prolonged cleaning effects. Innovations in microbial encapsulation, as noted by Novozymes, have further enhanced Bacillus-based formulations, improving their integration into cleaning products. The dominance of Bacillus is also driven by its alignment with eco-friendly detergent systems, which are gaining traction in sustainable cleaning solutions.

• The liquid form is predicted to gain substantial market share

Probiotic cleaning products are available in various forms, including powder, liquid, and others (e.g., gels or sprays). Liquid formulations lead the market due to their ease of use, versatility, and compatibility with consumer preferences.

Liquid probiotic cleaners dominate the market due to their convenience, widespread applicability, and compatibility with spray bottles, mops, and automated cleaning systems. Liquids allow for precise dosing and uniform application, making them popular in both household and commercial settings. Their formulations often incorporate stabilized Bacillus strains, which maintain viability in liquid suspensions, as highlighted by Azelis in their 2024 article on probiotic cleaning advancements. Liquid cleaners are particularly favored in healthcare and hospitality, where quick application and residue-free cleaning are critical. For instance, Unilever’s new Cif Infinite Clean, a liquid probiotic spray, underscores the growing consumer preference for ready-to-use solutions that combine efficacy with sustainability. Liquids also benefit from advancements in stabilization technologies, ensuring microbial activity over extended periods, enhancing their market appeal.

• By end-user, the household sector is gaining a large market share

The market serves various end-users, including households, hospitals, food and beverage industries, and others (e.g., schools and offices). The household segment is the largest due to widespread consumer adoption and increasing demand for eco-friendly products.

The household segment leads the US probiotics-based cleaning supplies market, driven by consumer demand for non-toxic, eco-friendly, and allergen-friendly cleaning solutions. With heightened awareness of health risks associated with chemical cleaners, households are increasingly adopting probiotic products for daily cleaning tasks, such as surface wiping, laundry, and odor control. A 2025 McKinsey survey noted that around 60% of US consumers prioritize sustainable household products, boosting demand for probiotic cleaners. These products appeal to families with children, pets, or allergy sufferers, as they reduce exposure to harsh chemicals and VOCs. The EPA’s Safer Choice program further supports household adoption by certifying probiotic cleaners that meet stringent environmental and safety standards. Retail availability of liquid probiotic sprays and wipes has also driven household penetration. The segment’s growth is further fueled by marketing campaigns emphasizing health and sustainability, positioning probiotic cleaners as a premium yet accessible choice for modern households.

US Probiotics-Based Cleaning Supplies Market Key Developments:

• Unilever’s Cif Infinite Clean Spray: In April 2025, Unilever introduced Cif Infinite Clean, a multi-usage spray combining 100% natural probiotics with effective cleaning ingredients. This product, aimed at the household market, leverages probiotic technology to provide prolonged cleaning action and odor control.
• Clean Habits’ Synbio Formula: Clean Habits, a US-based startup, launched its Synbio cleaning formula in July 2024, a patented blend of prebiotics and probiotics aimed at providing sustainable cleaning solutions. The product line, targeting household and commercial markets, emphasizes biodegradability and reduced environmental impact.
• Lively by Faultless Brands: In March 2023, Faultless Brands launched Lively, a line of probiotic household cleaners and pet care products designed to tackle dirt, odors, and harmful bacteria. These products, formulated with probiotic bacteria, cater to eco-conscious consumers seeking non-toxic cleaning solutions for homes and pet environments.
• Betco’s Probiotic Cleaning Program Launch: Betco, a leading US cleaning solutions provider, introduced a comprehensive probiotic cleaning program in October 2022, replacing traditional chemical cleaners with natural, non-toxic, and biodegradable formulations. The program includes products for hard surfaces, drains, and restrooms, utilizing Bacillus strains to reduce organic buildup and odors.

Segmentation:

• BY ORGANIC SOURCE
  • Lactobacillus
  • Other Bacillus Strains
• BY FORM
  • Powder
  • Liquid
  • Others
• BY END-USER
  • Household
  • Hospitals
  • Food and beverages
  • Others

1. EXECUTIVE SUMMARY 

2. MARKET SNAPSHOT

2.1. Market Overview

2.2. Market Definition

2.3. Scope of the Study

2.4. Market Segmentation

3. BUSINESS LANDSCAPE 

3.1. Market Drivers

3.2. Market Restraints

3.3. Market Opportunities 

3.4. Porter’s Five Forces Analysis

3.5. Industry Value Chain Analysis

3.6. Policies and Regulations 

3.7. Strategic Recommendations 

4. US PROBIOTICS-BASED CLEANING SUPPLIES MARKET BY ORGANIC SOURCE

4.1. Introduction

4.2. Lactobacillus 

4.3. Other Bacillus Strains

5. US PROBIOTICS-BASED CLEANING SUPPLIES MARKET BY FORM

5.1. Introduction

5.2. Powder

5.3. Liquid

5.4. Others

6. US PROBIOTICS-BASED CLEANING SUPPLIES MARKET BY END-USER

6.1. Introduction

6.2. Household

6.3. Hospitals 

6.4. Food and beverages 

6.5. Others

7. COMPETITIVE ENVIRONMENT AND ANALYSIS

7.1. Major Players and Strategy Analysis

7.2. Emerging Players and Market Lucrativeness

7.3. Mergers, Acquisitions, Agreements, and Collaborations

7.4. Competitive Dashboard

8. COMPANY PROFILES

8.1. Betco Corporation

8.2. Novozymes

8.3. Faultless Brands

8.4. Unilever 

8.5. Clean Habits

8.6. EnviroZyme

Betco Corporation

Novozymes

Faultless Brands

Unilever 

Clean Habits

EnviroZyme