Cell Cryopreservation Market Size, Share, Opportunities, And Trends By Product (Cell Freezing Media, Equipment, Consumables), By Application (Stem Cells, Oocytes And Embryotic Cells, Sperm Cells, Hepatocytes, Others), By End Use (Biopharmaceutical & Pharmaceutical Companies, Research Institutes, Biobanks, Ivf Clinics, Others), And By Geography - Forecasts From 2024 To 2029

  • Published : Feb 2024
  • Report Code : KSI061616271
  • Pages : 146

The cell cryopreservation market is estimated to grow at a CAGR of 22.35% during the forecast period.

Cryopreservation is a technique that involves preserving organelles, cells, tissues, or other biological structures by subjecting them to extremely low temperatures. The applications of cryopreservation span various areas, including- preserving cells or organs; cryosurgery; applications in biochemistry and molecular biology; contributions to food sciences; relevance in ecology and plant physiology; and numerous medical applications, such as blood transfusion, bone marrow transplantation, artificial insemination, and in vitro fertilization (IVF).

Cryopreservation offers several advantages, including the ability to bank cells for human leukocyte antigen typing for organ transplantation, facilitating the safe transport of cells and tissues across different medical centers, and serving as a valuable resource for research into unknown transmissible diseases or pathogens. Notably, the first instance of embryo cryopreservation for fertility preservation occurred in the late 1990s, involving the application of a natural IVF cycle before chemotherapy in a woman diagnosed with breast cancer.

Market Drivers

  • Rise due to strategic partnerships and collaborations

Globally, strategic partnerships and collaborations play a pivotal role in driving growth and development in the cell cryopreservation market. These alliances allow companies to capitalize on complementary strengths and resources, fostering mutual benefits and providing a strategic pathway for achieving shared objectives amid a competitive landscape. For instance, in January 2022, Cryoport, Inc., a global leader in temperature-controlled supply chain solutions for the life sciences industry, announced a strategic partnership with Cell Matters, S.A. This collaboration aims to deliver end-to-end cryopreservation services for leukapheresis-derived therapies, supporting both autologous and allogeneic cell therapies.

The partnership includes the joint development of a commercial approach for marketing these services. This strategic relationship with Cell Matters not only enhances Cryoport Systems' consulting services but also contributes to ongoing innovation and the development of temperature-controlled packaging solutions tailored to market needs. These alliances and targeted acquisitions are strengthening Cryoport's comprehensive supply chain solutions, aligning with the evolving needs of the life sciences industry.

Further in June 2023, SCTbio, a full-service contract development and manufacturing organization (CDMO) specializing in cell-based therapy and viral vectors, collaborated with Cyto-care.eu GmbH, a company specializing in advanced solutions for cell therapy and regenerative medicine. The collaboration is focused on enhancing the quality of cryopreservation for cell therapy development in Europe.

The goal is to address the critical need for efficient collection, cryopreservation, quality control, and logistics capabilities of leukapheresis materials, supporting various aspects of the cell therapy workflow. This partnership underscores the industry's commitment to advancing cryopreservation techniques and ensuring the seamless integration of cell therapies into the healthcare landscape.

  • New Scientific developments driving the field

In the rapidly advancing field of cell cryopreservation, ongoing scientific developments are reshaping the landscape with increasing frequency. The potential applications of cryopreservation are vast and continually expanding. Current research in this realm is particularly focused on the preservation of whole organs for extended storage and sustained viability, presenting a significant frontier in medical advancement. As it stands, organs like the heart, liver, and pancreas can endure only a few hours outside the body.

Cryopreservation holds the promise of substantially extending this critical timeframe to several days or even longer. Such breakthroughs could revolutionize organ transplantation procedures, mitigating logistical challenges and potentially saving more lives.

A key facet of these advancements lies in the development of new cryoprotectants—substances crucial for shielding cells from damage during the freezing and thawing process. Another pivotal development involves vitrification, a technique that freezes cells so rapidly that they assume a glass-like state rather than forming ice crystals. This innovative approach holds promise in reducing cell damage during freezing and thawing. Recognizing that thawing cells can be as detrimental as freezing them, novel thawing methods are also under development.

In essence, the dynamic landscape of cell cryopreservation is marked by the continuous development of scientific breakthroughs, unlocking new possibilities for organ preservation, improving cryoprotectant efficacy, enhancing methods, and refining the delicate process of thawing cells. These advancements collectively contribute to the ongoing evolution of cryopreservation technologies with profound implications for medical science and healthcare practices.

Market Challenges

  • High cost associated with the application

Cryopreserving cells, especially in large-scale applications, pose significant financial challenges due to expenses associated with cryoprotectants, storage facilities, and specialized equipment. The procurement costs of crucial cryoprotectants, essential for safeguarding cells during freezing, contribute to the overall expenditure. Advanced storage facilities with controlled environments add further to the costs.

Specialized equipment required for precise freezing and thawing processes also factors into the financial considerations of cell cryopreservation. To address these challenges, the integration of artificial intelligence (AI) emerges as a transformative solution. AI's benefits include enhancing safety measures and optimizing the storage conditions of biological materials, presenting a potential for cost-effective improvements in cryopreservation practices.

By application, the cell cryopreservation market is segmented into  stem cells, oocytes and embryotic cells, sperm cells, hepatocytes, and others

The cell cryopreservation market is strategically segmented, into specific applications. Stem cell cryopreservation holds promise for regenerative medicine, oocytes, and embryotic cell preservation supports assisted reproductive technologies, sperm cell cryopreservation aids fertility preservation, and Hepatocyte preservation facilitates drug research. The "others" category underscores cryopreservation's versatile applications. Altogether, these segments highlight cryopreservation's diverse contributions to regenerative medicine, reproductive health, and scientific research.

Europe is anticipated to hold a significant share of the Cell Cryopreservation Market

Europe is anticipated to play a significant role in the cell cryopreservation market, with the region being influenced by an exploration of cryopreservation practices within contemporary societies. This exploration is led by “CRYOSOCIETIES”, a project delving into the transformative impact of cryopreservation on temporalities and the fundamental concept of life. “CRYOSOCIETIES” is structured into four subprojects, each contributing to a comprehensive understanding of the creation of "suspended life" through ethnographic studies and theoretical frameworks.

The first subproject focuses on the storage of cord blood in Germany. The second subproject investigates the freezing of oocytes in Spain, exploring the motivations behind women's decisions to preserve their eggs and the role of oocyte cryopreservation within reproductive clinics and the broader reproductive sector. The third subproject concentrates on the cryopreservation of endangered or extinct species in the UK, particularly the initiatives of the Frozen Ark charity and the CryoArks biobank.

Complementing these empirical studies, the fourth subproject takes a theoretical approach, examining the implications of "suspended life." This theoretical exploration seeks to unravel the temporal and spatial regimes associated with various cryopreservation practices. In essence, the “CRYOSOCIETIES” project offers a multifaceted examination of cryopreservation within European contexts, shedding light on its diverse applications—from regenerative therapies to reproductive futures and conservation efforts for endangered species.

Market Developments

  • May 2022- OrganaBio, LLC,  inaugurated a cutting-edge laboratory facility in Irvine, California, marking an expansion of its presence and capabilities from the southeast to the west coast. This new establishment is poised to provide comprehensive support services to clinical trial sponsors and Contract Research Organizations (CROs). The services encompass patient sample processing, analytical testing, cryopreservation, and storage. Leveraging OrganaBio's advanced techniques in cell isolation, characterization, and cryopreservation, the Irvine facility will replicate its success in collecting and processing patients' samples. The facility will incorporate state-of-the-art storage systems to ensure optimal preservation and long-term storage of samples.
  • December 2021- AMSBIO inaugurated a new office in Alkmaar, Netherlands, with the establishment of AMSBIO Europe BV. This strategic move is geared towards providing European customers swift and convenient access to the company's extensive range of high-quality products and consumables. Recognizing the significance of the European market, AMSBIO has long been planning measures to ensure that EU researchers can seamlessly receive next-day delivery of products without customs delays, import tariffs, or the need for additional documentation. The newly established AMSBIO Europe BV office is designed to streamline operations and maintain local stock, allowing EU customers to order and receive the company's market-leading life science products efficiently and at reduced costs.
  • October 2022- FUJIFILM Irvine Scientific, Inc., a prominent global player in the realm of serum-free and chemically defined cell culture media for bioproduction and cell therapy manufacturing, unveiled a noteworthy development. The company announced that its PRIME-XV Stem FreezIS DMSO-Free cryopreservation medium has been selected as an excipient for an FDA-authorized clinical trial led by Vitro Biopharma. In this clinical trial, spearheaded by Vitro Biopharma, the primary objective is to explore both the safety and efficacy of intravenous infusions of their stem cell therapy product. The utilization of FUJIFILM Irvine Scientific's cryopreservation medium in this trial underscores the critical role it plays in maintaining the integrity and viability of stem cells, contributing to the success of advanced therapies and their potential applications in medical treatments.

Company Products

  • Cell Cryopreservation Solutions (Irvine Scientific)-  FUJIFILM Irvine Scientific's cell cryopreservation solutions are meticulously crafted as chemically defined and protein-free formulations, produced in strict adherence to cGMP standards. PRIME-XV FreezIS cryopreservation products facilitate the freezing of diverse cell types, such as human mesenchymal stem cells (MSCs) and human T cells. Following cryogenic preservation, thorough validation is conducted, assessing cell markers, viability, and fold expansion. The PRIME-XV FreezIS cryopreservation solutions employ a gradual freezing process, effectively minimizing potential damage arising from cold shock.
  • Cell Freezing Media and Salt-Based Solutions(Sartorius)-  Sartorius presents biopreservation solutions encompassing both short-term cold storage and extended cryopreservation with its Cell Freezing Media and Salt-Based Solutions. Tailored for the preservation of cells, including delicate varieties like stem cells, T cells, and PBMCs, NutriFreez® cell freezing, and NutriStor®. These solutions ensure the provision of animal component-free (ACF) conditions during biopreservation, crucial for maintaining uniformity when cultivating cells in xeno-free and ACF systems. Demonstrating established reliability and steadfast consistency, NutriFreez® and NutriStor® exhibit a notable performance and recovery rate following processes such as cold storage, freezing, and thawing.
  • Cryopreservation Of Cell Lines (Sigma-Aldrich) - Merck KGaA, Darmstadt, specializes in the cryopreservation of cell lines, offering several advantages. These include a diminished risk of microbial contamination, a lowered likelihood of cross-contamination with other cell lines, and a reduced risk of genetic drift and morphological changes. The work is performed using cells at a consistently maintained passage number. This approach not only enhances overall efficiency but also contributes to reduced costs, encompassing consumables and staff time.                     

Cell Cryopreservation Market Scope:


Report Metric Details
Growth Rate CAGR of 22.35% from 2022 to 2029
Base Year 2022
Forecast Period 2024 – 2029
Forecast Unit (Value) USD Billion
Segments Covered
  • Product
  • Application
  • End Use
  • Geography
Companies Covered
Regions Covered North America, South America, Europe, Middle East and Africa, Asia Pacific
Customization Scope Free report customization with purchase


Market Segmentation

  • By Product   
    • Cell Freezing Media
    • Equipment
    • Consumables
  • By Application
    • Stem Cells
    • Oocytes And Embryotic Cells
    • Sperm Cells
    • Hepatocytes
    • Others
  • By End Use
    • Biopharmaceutical & Pharmaceutical Companies
    • Research Institutes
    • Biobanks
    • Ivf Clinics
    • Others
  • By Geography
    • North America
      • USA
      • Canada
      • Mexico
    • South America
      • Brazil
      • Argentina
      • Others
    • Europe
      • UK
      • Germany
      • France
      • Spain
      • Others
    • Middle East and Africa
      • Saudi Arabia
      • UAE
      • Israel
      • Others
    • Asia Pacific
      • China
      • Japan
      • South Korea
      • India
      • Indonesia
      • Thailand
      • Others


1.1. Market Overview

1.2. Market Definition

1.3. Scope of the Study

1.4. Market Segmentation

1.5. Currency

1.6. Assumptions

1.7. Base, and Forecast Years Timeline


2.1. Research Data

2.2. Assumptions


3.1. Research Highlights


4.1. Market Drivers

4.2. Market Restraints

4.3. Porter’s Five Force Analysis

4.3.1. Bargaining Power of Suppliers

4.3.2. Bargaining Power of Buyers

4.3.3. Threat of New Entrants

4.3.4. Threat of Substitutes

4.3.5. Competitive Rivalry in the Industry

4.4. Industry Value Chain Analysis


5.1. Introduction

5.2. Cell Freezing Media

5.3. Equipment

5.4. Consumables


6.1. Introduction

6.2. Stem Cells

6.3. Oocytes and Embryotic Cells

6.4. Sperm Cells

6.5. Hepatocytes

6.6. Others


7.1. Introduction

7.2. Biopharmaceutical & Pharmaceutical Companies

7.3. Research Institutes

7.4. Biobanks

7.5. IVF Clinics

7.6. Others


8.1. Introduction

8.2. North America

8.2.1. United States

8.2.2. Canada

8.2.3. Mexico

8.3. South America

8.3.1. Brazil

8.3.2. Argentina

8.3.3. Others

8.4. Europe

8.4.1. United Kingdom

8.4.2. Germany

8.4.3. France

8.4.4. Spain

8.4.5. Others

8.5. The Middle East and Africa

8.5.1. Saudi Arabia

8.5.2. UAE

8.5.3. Israel

8.5.4. Others

8.6. Asia Pacific

8.6.1. Japan

8.6.2. China

8.6.3. India

8.6.4. South Korea

8.6.5. Indonesia

8.6.6. Thailand

8.6.7. Others


9.1. Major Players and Strategy Analysis

9.2. Market Share Analysis

9.3. Mergers, Acquisitions, Agreements, and Collaborations


10.1. Irvine Scientific

10.2. Biogenuix

10.3. Cryo-Cell

10.4. Sartorius

10.5. Sigma-Aldrich

10.6. Cytiva

10.7. AMSBIO

10.8. Cocoon Hospital

10.9. Charles River Laboratories

10.10. Transgen Biotech

Irvine Scientific







Cocoon Hospital

Charles River Laboratories

Transgen Biotech