The Calcifediol Supplements Market is expected to grow at a CAGR of 9.21%, reaching a market size of US$2,189.3 million in 2030 from US$1,409.4 million in 2025.
Calcifediol is an active form of Vitamin D found in the bloodstream, also known as 25-hydroxyvitamin D3. It is produced by the liver by hydroxylation of Vitamin D3 that we get from sunlight or diet. It is used to measure the Vitamin D level in the body.
Calcifediol supplements are a more advanced and powerful type of vitamin D supplement. It has been clinically demonstrated to increase vitamin D levels three times quicker and more efficiently than other methods. Calcifediol monohydrate (25-Hydroxyvitamin D3) is a vitamin D3 analogue created by hydroxylation of vitamin D3 (cholecalciferol) using the enzyme cholecalciferol 25-hydroxylase.
The increasing Vitamin D deficiency worldwide and the aging population are driving the market growth for its supplements. Calcifediol is a better alternative than other forms of Vitamin D supplements as it is absorbed more quickly and increases Vitamin D levels by 3 times in the body, thus leading to an increase in its demand. Moreover, its usage in treating secondary hyperparathyroidism, managing hypocalcemia, and preventing osteoporosis would help in increasing the calcifediol supplements market growth.
Globally, there is an increase in the number of people with Vitamin D deficiency. At the same time, the number of geriatric populations is on the rise worldwide. These factors are creating demand for Vitamin D supplements. Calcifediol is a superior alternative to other vitamin D supplements. It offers an effective solution for addressing vitamin D deficiency, providing a faster and more efficient method to raise vitamin D levels than traditional vitamin D3 supplements.
As per a study done by the National Center of Biotechnology Information, there are 76.6% of participants had serum 25-hydroxyvitamin D deficiency below 75 nmol/l, showing a higher prevalence of deficiency of vitamin D. Globally, approximately 30-45% of people have vitamin D deficiency, making it around 1 billion people.
The health and fitness sector is experiencing significant market growth as a greater number of people are becoming aware of their health, especially post-pandemic. The demand for dietary supplements is increasing as people prioritize their health and wellness by supplementing their bodies with micronutrients. Calcifediol Vitamin D Supplement effectively fights vitamin D deficiency and other related problems by increasing vitamin D levels in the blood, thus helping to boost immunity and bone health.
According to a study done by the American Medical Association, between 1994 and 2017, there is an increase in dietary supplements by 86,000 from 4000 to 90,000 products. More than half of the US adults consume dietary supplements, indicating an increased health awareness among the population. The increased awareness among people for vitamin D supplements would act as a market driving force for the Calcifediol Supplement market.
On the basis of applications where Calcifediol Supplement is used to treat, it is segmented into Vitamin D deficiency, Osteoporosis, Secondary hyperparathyroidism, and others.
During the forecast period, this supplement would be dominated by using it in treating Vitamin D deficiency. Calcifediol is primarily made for supplementing the body with Vitamin D by releasing faster and more efficient vitamin D in the body.
Region-wise, the global market is segmented into Asia-Pacific, North America, South America, Europe, Middle East and Africa. North America would hold the largest market share for Calcifediol supplements in the forecast period.
North America is experiencing a demographic shift towards the older population. In the United States of America, there are around 77 million people aged above 65, according to the U.S. Census Bureau Project. In Canada, the aging population is increasing, too. Vitamin D deficiency in the aging population, coupled with deficiency in a great number of adults, would significantly increase the demand for calcifediol supplements in the North American region. Though all the regions are facing the issue of vitamin D deficiency, North America, particularly the United States of America, would have the highest growth in the calcifediol supplement market as there are increasing trends among people for dietary supplements and the prevalence of advanced healthcare infrastructure coupled with significant innovations and the advancement in the health sector.
Though the calcifediol supplement is a better and more advanced alternative for Vitamin D deficiency, the awareness of Calcifediol as a vitamin D supplement is limited when compared to other vitamin D supplements. This limited awareness is a limiting factor in the Calcifediol supplement market growth. Creating more awareness about the product and its advantages over traditional vitamin D supplements can effectively mitigate the restraint and can lead to significant market growth for Calcifediol Supplements.
| Report Metric | Details |
|---|---|
| Study Period | 2021 to 2031 |
| Historical Data | 2021 to 2024 |
| Base Year | 2025 |
| Forecast Period | 2026 – 2031 |
| Report Metric | Details |
| Calcifediol Supplements Market Size in 2025 | US$1,409.4 million |
| Calcifediol Supplements Market Size in 2030 | US$2,189.3 million |
| Growth Rate | CAGR of 9.21% |
| Study Period | 2020 to 2030 |
| Historical Data | 2020 to 2023 |
| Base Year | 2024 |
| Forecast Period | 2025 – 2030 |
| Forecast Unit (Value) | USD Million |
| Segmentation |
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| Geographical Segmentation | North America, South America, Europe, Middle East and Africa, Asia Pacific |
| List of Major Companies in the Calcifediol Supplements Market |
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| Customization Scope | Free report customization with purchase |