Homozygous Familial Hypercholesterolemia (HoFH) Pipeline Analysis 2018 - Focusing On Clinical Trials And Results, Drug Profiling, Patents, Collaborations, And Other Recent Developments

  • Published : Mar 2020
  • Report Code : KSI061611440
  • Pages : 114

Homozygous Familial Hypercholesterolemia (HoFH) Pipeline Analysis report covers 7 drugs currently in different phases of development. HoFH is an inherited rare disorder characterised by difficult lipoprotein metabolism and extremely high level of circulating low density lipoprotein cholesterol (ranging between 500 and 1200 mg/dl.). These high level of cholesterol accumulates in the arteries leading to cardiovascular disease much faster than in the normal population. The disease is caused due to the mutation of both alleles of the LDL-receptor (LDLR) gene. Clinical manifestations of the HoFH incliclude elevated levels of LDLC, xanthomata and premature cardiovascular disease.

The report provides Homozygous Familial Hypercholesterolemia (HoFH) treatment drugs by company, phases of development including products in early discovery stage and NDA filing, molecule type, route of administration and region. The report will help to evaluate the collaboration, in-licensing and out-licensing opportunities, formulating business development strategies and tracking the activities of the key market players. Epidemiology, major drivers, restraints, and opportunities have been covered to provide an exhaustive picture of the market. The analysis presents in-depth information regarding the development, trends, and industry policies and regulations implemented to offer stakeholders a better understanding of the key factors affecting the overall market environment.

Various databases (for patents and Clinical Trials), studies and data published by industry associations, analyst reports, investor presentations, press releases and journals among others have been taken into consideration while conducting the secondary research.

Market intelligence is presented in the form of analysis, charts, and graphics to help the clients in gaining faster and efficient understanding of the market.

Major industry players profiled as part of the report are Akcea Therapeutics, Regeneron Pharmaceuticals Inc. and The Medicines Company among others.

Scope:

By Company

By Phase

By Molecule Type

By Region

By Route of Administration


1. Introduction

1.1. Research Methodology

1.2. Research Scope

1.2.1. Analysis by Company

1.2.2. Analysis by Phase

1.2.3. By Molecule Type

1.2.4. By region

2. Disease Overview

2.1.1. Introduction

2.1.2. Classification

2.1.3. Symptoms

2.1.4. Causes

2.1.5. Diagnoses

2.1.6. Treatment

2.1.7. Epidemiology

3. Executive Summary

4. Market Dynamics

4.1. Drivers

4.2. Restraints

4.3. Opportunities

5. Pipeline Analysis/Outlook

5.1. Analysis by Company

5.2. Analysis by Phase

5.2.1. Phase of Development

5.2.1.1. Introduction

5.2.1.1.1. Drug Profiling

• Drug Name

• Generic Name

• Synonyms

• Company

• Collaborator

• Route of administration

• Target

• Mechanism of Action

• Technology

• Molecule type

• CAS Number

• Weight

• Chemical Formula

• IUPAC name

• ATC code

5.2.1.1.2. Strategic Developments

5.2.1.1.3. Clinical trials

5.2.1.1.4. Clinical trial results

5.2.1.1.5. Patents

5.2.1.1.6. Technology

5.2.2. Comparative Analysis for Trials by Phase (Pie, Bar graph)

5.3. By Molecule type

5.4. Analysis by Region

6. Company profiling

6.1. Akcea Therapeutics

6.1.1. Introduction

6.1.2. Financials

6.1.3. Products and Services

6.1.4. SWOT

6.2. Gemphire

6.2.1. Introduction

6.2.2. Financials

6.2.3. Products and Services

6.2.4. SWOT

6.3. LipimetiX, Inc.

6.3.1. Introduction

6.3.2. Financials

6.3.3. Products and Services

6.3.4. SWOT

6.4. Regeneron Pharmaceuticals Inc.

6.4.1. Introduction

6.4.2. Financials

6.4.3. Products and Services

6.4.4. SWOT

6.5. Regenxbio Inc.

6.5.1. Introduction

6.5.2. Financials

6.5.3. Products and Services

6.5.4. SWOT

6.6. The Medicines Company

6.6.1. Introduction

6.6.2. Financials

6.6.3. Products and Services

6.6.4. SWOT

6.7. Akeso

6.7.1. Introduction

6.7.2. Financials

6.7.3. Products and Services

6.7.4. SWOT

List of Tables

List of Figures


Akcea Therapeutics

Gemphire

LipimetiX, Inc.

Regeneron Pharmaceuticals Inc.

Regenxbio Inc.

The Medicines Company

Akeso